| IED ID | IndEnz0002011306 |
| Enzyme Type ID | protease011306 |
| Protein Name |
Aspartic proteinase yapsin-7 EC 3.4.23.- |
| Gene Name | YPS7 YDR349C |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Saccharomycotina (true yeasts) Saccharomycetes Saccharomycetales Saccharomycetaceae Saccharomyces Saccharomyces cerevisiae (Baker's yeast) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
| Enzyme Sequence | MTCLILWYLWLISTFQLEFATASTANTTTTAKSGTSSSTEEPFPVLAVGKDGRGNYYVNSTFGTPGQRQRLLVDIIQPYINLVSGTSESHNEYSGVYHKHPSYLMNDSTSSVPVSPGQIYEISFIDGRAVNCTLVTDDMNFTNVSSENSSTALITDLMVTRDNVQFNSGSLSISNVSFFDIQSSNFKTSGLLGLSGKVTNPGNAIDSSQYTEQSYFLSLLKDADIIESSSYSLWLAGDTSTYKTYRDPISNCGKLLLGGVDPSLFTGTLGKFDLIPYVDPVSNAVSVGYPIVPLGPIYIVSNSGQSLNMTSKDFLSPALLDSTSSVSYLPTSTIIQIAVQIAATYVESLDRWLVQCSIADMGVSLGFRLRELTIEIPLRDLLSSTYDTSTNSSMFFSSGQEACFLTLYANTNTGVNILGEAFIKNIYMAMDLEDNTIAIAQAKKVEDDAVTEETNETTASTIIKKIKSGYIPYAKVMNSSNTRNLTLYPSYRSGYMFTVPGQLTAAYSNGVITGAGRSFYDTSRASTSARPSSTQFDSFSVSASEEWSNSTNRTSSASGAGVRLSSPYTFNKDPAGHVTRIASLLLLSIFSILIVL |
| Enzyme Length | 596 |
| Uniprot Accession Number | Q06325 |
| Absorption | |
| Active Site | ACT_SITE 74; /evidence=ECO:0000250; ACT_SITE 321; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.23.- |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Domain (1); Glycosylation (15); Sequence conflict (1); Signal peptide (1); Topological domain (1); Transmembrane (1) |
| Keywords | Cytoplasm;Endoplasmic reticulum;Glycoprotein;Hydrolase;Membrane;Protease;Reference proteome;Signal;Transmembrane;Transmembrane helix |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:14562095}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:14562095}; Single-pass type I membrane protein {ECO:0000269|PubMed:14562095}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..25; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 10191273; 17042746; 20599573; 21810245; 21936842; 22162039; 27693354; 27965112; |
| Motif | |
| Gene Encoded By | |
| Mass | 64,498 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |