Detail Information for IndEnz0002011352
IED ID IndEnz0002011352
Enzyme Type ID protease011352
Protein Name Kunitz-type serine protease inhibitor hainantoxin F7-25.66
Peptide F7-25.66
Fragment
Gene Name
Organism Cyriopagopus hainanus (Chinese bird spider) (Haplopelma hainanum)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Chelicerata Arachnida Araneae (spiders) Mygalomorphae (mygalomorph spiders) Theraphosidae (tarantulas) Haplopelma Cyriopagopus hainanus (Chinese bird spider) (Haplopelma hainanum)
Enzyme Sequence IDTCRLPSDRGRCKASFERWYFNGRTCAKFIYG
Enzyme Length 33
Uniprot Accession Number P0CH75
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Serine protease inhibitor that inhibits trypsin and blocks voltage-gated potassium channels (Kv). {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Domain (1); Non-terminal residue (1); Peptide (1); Site (1)
Keywords Direct protein sequencing;Ion channel impairing toxin;Potassium channel impairing toxin;Protease inhibitor;Secreted;Serine protease inhibitor;Toxin;Voltage-gated potassium channel impairing toxin
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 3,918
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda