| IED ID | IndEnz0002011366 |
| Enzyme Type ID | protease011366 |
| Protein Name |
WAP four-disulfide core domain protein 12 Putative protease inhibitor WAP12 Whey acidic protein 2 |
| Gene Name | WFDC12 C20orf122 WAP2 UNQ544/PRO844 |
| Organism | Homo sapiens (Human) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Primates Haplorrhini Simiiformes Catarrhini Hominoidea (apes) Hominidae (great apes) Homininae Homo Homo sapiens (Human) |
| Enzyme Sequence | MGSSSFLVLMVSLVLVTLVAVEGVKEGIEKAGVCPADNVRCFKSDPPQCHTDQDCLGERKCCYLHCGFKCVIPVKELEEGGNKDEDVSRPYPEPGWEAKCPGSSSTRCPQK |
| Enzyme Length | 111 |
| Uniprot Accession Number | Q8WWY7 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Antibacterial protein. Putative acid-stable proteinase inhibitor. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Disulfide bond (4); Domain (1); Region (1); Signal peptide (1) |
| Keywords | Antibiotic;Antimicrobial;Disulfide bond;Protease inhibitor;Reference proteome;Secreted;Serine protease inhibitor;Signal |
| Interact With | Q12797-6; O43765; Q96EQ0; Q92504; Q9UMX0; Q9UHD9 |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..23; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 33157095; |
| Motif | |
| Gene Encoded By | |
| Mass | 12,050 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |