| IED ID | IndEnz0002011639 |
| Enzyme Type ID | protease011639 |
| Protein Name |
26S proteasome regulatory subunit 6B homolog 26S protease subunit 6B homolog 26S proteasome AAA-ATPase subunit RPT3 Protein BMAA insensitive morphology 409 Regulatory particle triple-A ATPase subunit 3 |
| Gene Name | RPT3 BIM409 At5g58290 MCK7.16 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
| Enzyme Sequence | MASAAVASMVLDPKASPALMDLSTADEEDLYGRLKSLERQLEFTDIQEEYVKDEQKNLKRELLRAQEEVKRIQSVPLVIGQFMEMVDQNNGIVGSTTGSNYYVRILSTINRELLKPSASVALHRHSNALVDVLPPEADSSISLLSQSEKPDVSYNDIGGCDIQKQEIREAVELPLTHHELYKQIGIDPPRGVLLYGPPGTGKTMLAKAVANHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEVDAIATARFDAQTGADREVQRILMELLNQMDGFDQTVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLVFQVCTSKMNLSDEVDLEDYVSRPDKISAAEIAAICQEAGMHAVRKNRYVILPKDFEKGYRANVKKPDTDFEFYK |
| Enzyme Length | 408 |
| Uniprot Accession Number | Q9SEI4 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. {ECO:0000269|PubMed:19412571}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | NP_BIND 196..203; /note=ATP; /evidence=ECO:0000255 |
| Features | Chain (1); Coiled coil (1); Initiator methionine (1); Modified residue (2); Mutagenesis (1); Nucleotide binding (1) |
| Keywords | ATP-binding;Acetylation;Coiled coil;Cytoplasm;Nucleotide-binding;Nucleus;Phosphoprotein;Proteasome;Reference proteome |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
| Modified Residue | MOD_RES 2; /note=N-acetylalanine; /evidence=ECO:0007744|PubMed:22223895; MOD_RES 16; /note=Phosphoserine; /evidence=ECO:0007744|PubMed:19245862 |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 10363660; 11742986; 15829605; 16287169; 17432890; 17825468; 18160300; 18650403; 18775970; 20118269; 20706207; 21798944; 23281391; 24529374; 32753431; 9741626; |
| Motif | |
| Gene Encoded By | |
| Mass | 45,751 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda | 5.6.1.5; |