| IED ID | IndEnz0002011695 |
| Enzyme Type ID | protease011695 |
| Protein Name |
Aspartic proteinase sxa1 EC 3.4.23.- |
| Gene Name | sxa1 SPAC26A3.01 SPAC2E1P5.06 |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota Taphrinomycotina Schizosaccharomycetes Schizosaccharomycetales Schizosaccharomycetaceae Schizosaccharomyces Schizosaccharomyces pombe (Fission yeast) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
| Enzyme Sequence | MKASFFVFAISALQALQASVASAYSEVPGKRSVVLNLQHSQYDHVARKLERTKVLNKRDSSGYPVLDLEYTDAGGYFANLTLGSNERVYSLTLDTGSPYTWVTAKNITALSASEIWSDTDGVDAGRSTSDIRTNACTNYTCFDYSSTTARRTNSSTIGFLASYGDNTTVLGYNMVDNAYFAGLTLPGFEFGLATREYDSSQISVTPGIIGLSVAMTITGISSDDKVVAFTPPTIVDQLVSANVIDTPAFGIYLNEDVGELIFGGYDKAKINGSVHWVNISSSDDSTFYSVNLESITVTNSTSSNNVQSSKRSSKDIEVNTTVTLDTGTVYIYLPEDTVESIADQYQGIVSEYGYVVIYCDSFSDSDYISFNFGSDADFHVSVNDLVIYRQESTSGDICYLALFEGDTSSYLLGQYFLQYVYSIYDWDAQKIGLAALNSNATSTANHQILNINSALRSVTSGQSVSATPTVSMSIAATSFGSSLVLTASASPSSTSVDGSSSSDSSEASGAASVGVSISAIVLCASTLISLLFA |
| Enzyme Length | 533 |
| Uniprot Accession Number | P32834 |
| Absorption | |
| Active Site | ACT_SITE 94; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094; ACT_SITE 325; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.23.- |
| Enzyme Function | FUNCTION: Involved in degradation or processing of the mating pheromones. Its loss may cause a persistent response to the pheromones. It may cleave the mating pheromone M-factor. May be involved in processing of zymogens that are required for zygote formation. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Domain (1); Glycosylation (10); Sequence conflict (1); Signal peptide (1) |
| Keywords | Aspartyl protease;Glycoprotein;Hydrolase;Protease;Reference proteome;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..23; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 12845604; 20473289; 22633491; 23173672; 23697806; 25803873; 27918601; 30647105; 32101745; 34250083; 9191273; |
| Motif | |
| Gene Encoded By | |
| Mass | 56,853 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |