| IED ID | IndEnz0002011749 |
| Enzyme Type ID | protease011749 |
| Protein Name |
Thiol protease/hemagglutinin PrtT EC 3.4.22.- |
| Gene Name | prtT |
| Organism | Porphyromonas gingivalis |
| Taxonomic Lineage | cellular organisms Bacteria FCB group Bacteroidetes/Chlorobi group Bacteroidetes Bacteroidia Bacteroidales Porphyromonadaceae Porphyromonas Porphyromonas gingivalis |
| Enzyme Sequence | MKRIFYTLGLLLLCLPMLQAGPVTRSKAEQTAKNFFAKRQPTLSSSTASLRMDFVYKAAEREEALFFVFNRGEKDGFLLVAADDRFPEVIGYAFKGHFDAARMPDNLRGWLKGYEREMLAVMDGKAEPIDPIREAKPTRDLPSSIAPILETGEHASDPILWDQGYPFNTLHPLLPSGQQAYTGCVATAMGQIMRHYKWPEKASGEYDYYDDMTGTHTHYSGTFGETYNWSKMPGNISVGISPEEVKALSTFMRDVSFSVNMQFADFGSGTFSIFVERALRETFHYKKSLRYIHRSLLPGKEWKDMIRKELAENRPVYYAGADGSMGHAFVCDGYEPDGTFHFNWGWGGMSNGNFYLNLLNPGSLGTGAGDGGYSTDQEVVIGIEPASNEAPGIVPDPTITLYGLQHNMSDEALDLSVKIKNYSTYAGDVKLAYRLTLPNGTETTNPAVTVPIVWEDIIGESTGNITIPCSQFAEGKNTISILYRTDGMADWKELKHILMGLVNKIEVTMPAGDVAYSVADARIVLKDGSLSHNLKAYSDCKLSATVYNPGTEEFRSRVTFALRNTEGRLYFLGRHLVELHPGDEDGEKVSLTITGLKARAGQYMLVCTGDMELLMEDASWIELASIEVAEHTSTHSSLLVASNPQIDLLTVHRANPETLPTFSITNEGGATFSGKIEIVAIKAFSETFFQAKEEHMSLAQGETKVLSPELTANSSLYTNAELFPDGIYYIVIREQGFWDPIDLFGDYYYRIRLITDLSSSXIAGKDVSTIVLYPNPAHDYVHVAIPPTYAGSTLRLFDIQGRMQLSTKIRICRYASRRRTSSEGHLYRCGRRHGREALYSLIQSVNSKTDKGNAGWEIPSGHCPCTVC |
| Enzyme Length | 868 |
| Uniprot Accession Number | P43158 |
| Absorption | |
| Active Site | ACT_SITE 184; /evidence=ECO:0000250; ACT_SITE 327; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.22.- |
| Enzyme Function | FUNCTION: Appears to be specific for arginine-containing peptide bonds. Possesses hemagglutinin activity. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Propeptide (1); Signal peptide (1) |
| Keywords | Hemagglutinin;Hydrolase;Protease;Signal;Thiol protease |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..27; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 96,445 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |