| IED ID | IndEnz0002011961 |
| Enzyme Type ID | protease011961 |
| Protein Name |
Putative dipeptidyl aminopeptidase C2E11.08 EC 3.4.14.- |
| Gene Name | SPAC2E11.08 SPACUNK4.08 |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota Taphrinomycotina Schizosaccharomycetes Schizosaccharomycetales Schizosaccharomycetaceae Schizosaccharomyces Schizosaccharomyces pombe (Fission yeast) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
| Enzyme Sequence | MNDFSFEDKGLISRSGFGSRHVRRVVKALALIFSLLILYLTISNVSDSPPKRDSLSLDDIVLQKYKPSYKQVNWIDSQGLKDTFLVKYGDLINIQDPYNLNKTLFSVSDLVYNGIQLDYDSYSISFDAKYVLVSVNKSQRWRHSSFAQYYLYNTETKDVNMLGQDNEHWTISLAEWSPTGHQLSFVYNNDLYVRKNDGNVQRLTYDGTVDVFNGLTDWIYEEEVLSSPSTIWWSPDSDKIAFLKLNESEIPTYHYPLYTAELDPSLPEFDYNKDMAIKYPKPGNPNPSVSLFVADLNSNASSNFSLWHNEPLAEPVVQNVLWVNTSSVLVQFTNRNSTCITARLLDTELKSIHTVKTECLEEGWYEVQQSAKMFPLNNSLVWENWSDGYFDILALDDYNHLAFIPFNGSSPIYLTSGAWDVTDGPIHIDGDFGNVYFLATLKDSTERHLYYVSLDTLEIYGITDNGEDEGYYSTSFSPFGDFYVLNYHGPDVPWQELRSTKDKDYCLSLETNSRLKQQLSSITLPSVEYGKLTFNDTTFNFMERRPRNFDVNKKYPVLFFAYGGPGSQQVAKLFRVDFQAYLASHPDFEFIVVTLDGRGTGFNGNAFRYSVSRHLGEWESYDQGQAGKFWADLPFVDENHVGIWGWSYGGYLTLKTLETQDVFSYGMAVAPVTDWRLYDSVYTERYMDLPQYNKEGYKNSQIHDYEKFKQLKRFFVAHGTGDDNVHFQHSMHLMDGLNLANCYNYDMAVFPDSAHSISYHNASLSIYHRLSEWIGDALGRIDPSTGVRQHRWD |
| Enzyme Length | 793 |
| Uniprot Accession Number | O14073 |
| Absorption | |
| Active Site | ACT_SITE 647; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU10084; ACT_SITE 722; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU10084; ACT_SITE 755; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU10084 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.14.- |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Glycosylation (12); Topological domain (2); Transmembrane (1) |
| Keywords | Aminopeptidase;Glycoprotein;Hydrolase;Membrane;Protease;Reference proteome;Serine protease;Signal-anchor;Transmembrane;Transmembrane helix;Vacuole |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Note=Lysosome-like vacuoles. {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 20473289; 22633491; 23697806; 25803873; 30726745; |
| Motif | |
| Gene Encoded By | |
| Mass | 91,305 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |