| IED ID | IndEnz0002012054 |
| Enzyme Type ID | protease012054 |
| Protein Name |
Putative tricorn protease homolog 2 EC 3.4.21.- |
| Gene Name | tri2 SCO3168 SCE87.19 |
| Organism | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) |
| Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Actinobacteria Actinomycetia (high G+C Gram-positive bacteria) Streptomycetales Streptomycetaceae Streptomyces Streptomyces albidoflavus group Streptomyces coelicolor Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) |
| Enzyme Sequence | MRGARKSMGRVSYLRLPHLSGDQLCFVAEDDLWLASLDGPGRAWRLTVDRTKAGPPRFSPDGRHIAYTSWRTLVPEVHLVPVDGGPGRQLTHWGGLDTRVCGWSPPDPDGTTAVLAVASHGEPFSHLTWAYKVTPDGDPGRKLPWGPVTDIQAADLDGERRTLLLTGTPPHEPAAWKRYRGGATGRLWLHGERLLPDLGGHLSAPMFVGGRIAFLSDHEGVGNLYSCAQDGTGLRRHTDHDAFYARNAASDGTRVVYQCAGDLWIVDDLAPGSAPRRLDVRLSGPRAGRRTHQVPAAQHVGGISVDETGRASAVVVRGSLYWLTHRDGPARTIADTPGVRVRLPEMLGESGRIAYVTDAEGEDAVEISYLPRATGGRAARRLASGRLGRVLELVSDPAGDRLAVASHDGRLLILDVAEPDTEVTLALEAVDAGYPPDAGDEDAAGTAARADSAPDAPAEDTDARDIAAGTGTGDIADADAAAGGTVTPGSPGTPATAGGQVTELIRSVNGPVRDLAFSPDGTWLTWSHPGIGRTLRQIKMARIDGPEGTLVVDVTNGRFEDENPVFTRDGRYLAFLSWRGFDPVYDVHTGDLSFPLGCRPYLVPLSSATPSPFALNPEGRPAAGGLDPLEDEPGEGGAVMVEVEGLESRVTPFPVTASKYSALEPVAGGGLVWLRWPISGALGETFANPADPSERPTLEHFNLAKAKKSELVDHLDWFRVSGDGSRLVVLDEGELRAVPASEVGDGDSTTWIDLRRILHEVDPAAEWRQAYDEAGRLIRAYFWDPGMCGIDWDAVLDQYRPLLERVASPDEFADLLREVLGELGTSHAYVVAARRNEGPAHYQRWQGLLGANLACRDGRWLVRRILPGDSSDSKARSPLAGTGIRDGAVLTHVDGRPVDPVLGPSPLLAGAGGTTVELTFAPAEGCQGPSRRVAVVPLVDERPLRYQDWVAKRREVVRELSGGRCGYLHIPDMGGSGWAQFNRDLRMEVSRPALIVDVRGNAGGHISELVIEKLTRTILGWDLTRDAQPVSYTSNAPRGPVVAVADEATSSDGDMITAAFKLLRLGPVVGQRTWGGVVGMTGRHRLGDGSVITVPMNAAWFDAYGWSVENYGVAPDVEALRTPLDWAEGRYPVLDEAVRLALELLETNPPATPPGYEAVPDRSRPPLPPRE |
| Enzyme Length | 1171 |
| Uniprot Accession Number | Q9RKB9 |
| Absorption | |
| Active Site | ACT_SITE 827; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 1051; /note=Nucleophile; /evidence=ECO:0000250|UniProtKB:P96086; ACT_SITE 1109; /note=Charge relay system; /evidence=ECO:0000250|UniProtKB:P96086 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.21.- |
| Enzyme Function | FUNCTION: Degrades oligopeptides in a sequential manner. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Region (5); Site (1) |
| Keywords | Cytoplasm;Hydrolase;Protease;Reference proteome;Serine protease |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 125,661 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |