| IED ID |
IndEnz0002012077 |
| Enzyme Type ID |
protease012077 |
| Protein Name |
Kunitz-type serine protease inhibitor homolog beta-bungarotoxin B3 chain
|
| Gene Name |
|
| Organism |
Bungarus candidus (Malayan krait) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Metazoa
Eumetazoa
Bilateria
Deuterostomia
Chordata
Craniata
Vertebrata
Gnathostomata (jawed vertebrates)
Teleostomi
Euteleostomi
Sarcopterygii
Dipnotetrapodomorpha
Tetrapoda
Amniota
Sauropsida
Sauria (diapsids)
Lepidosauria (lepidosaurs)
Squamata (squamates)
Bifurcata (split-tongued squamates)
Unidentata
Episquamata
Toxicofera
Serpentes (snakes)
Colubroidea
Elapidae
Bungarinae
Bungarus
Bungarus candidus (Malayan krait)
|
| Enzyme Sequence |
MSSGGLLLLLGLLTLWAELTPVSSRKRHPDCDKPPDTRICQTVVRAFYYKPSEKRCVQFRYGGCKGNGNHFKSDHLCRCECLEYR |
| Enzyme Length |
85 |
| Uniprot Accession Number |
Q75S50 |
| Absorption |
|
| Active Site |
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| Activity Regulation |
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| Binding Site |
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| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Beta-bungarotoxin is a presynaptic neurotoxin of the venom. The B chain is homologous to venom basic protease inhibitors but has no protease inhibitor activity and is non-toxic (By similarity). {ECO:0000250}. |
| Temperature Dependency |
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| PH Dependency |
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| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Disulfide bond (4); Domain (1); Signal peptide (1) |
| Keywords |
Disulfide bond;Neurotoxin;Presynaptic neurotoxin;Secreted;Signal;Toxin |
| Interact With |
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| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Secreted {ECO:0000250}. |
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
SIGNAL 1..24; /evidence=ECO:0000250 |
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
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| Gene Encoded By |
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| Mass |
9,751 |
| Kinetics |
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| Metal Binding |
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| Rhea ID |
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| Cross Reference Brenda |
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