| IED ID | IndEnz0002012189 |
| Enzyme Type ID | protease012189 |
| Protein Name |
Probable aspartic-type endopeptidase AFUA_3G01220 EC 3.4.23.- |
| Gene Name | AFUA_3G01220 |
| Organism | Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Fumigati Neosartorya fumigata (Aspergillus fumigatus) Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) |
| Enzyme Sequence | MHFSIGSLFLYLIASASCTAASPQYIQRSRRTPFTTSTSKPSAFTNPSTDTATTPYVLELTKINNKGNARSAVELNSQVRSGSANLVSFAEGVGFATSINIGNQTFEVVIDTGSSDLWVVRDGFICIDPVSRKEVAQSECRFGPAYAPNTTFHEVVGEFVDIKYADGEILSGVIGTENVTLAGITVNQTIGVMDYAGWYGDGVTSGLMGLAYSSLASAYTTNNRQPRLYNPIFATMYEQGLIDPIFSMVMNRNASNGTAAGYLTLGGLPPVDINGNFSTTPILITNIKGYPKDYDFYAVNIDGVALGNRSLPEAAGGIQYIIDSGTTLNYYPTPVADSVNAAFIPPAVYNDYDGAYVVDCNATASVHGVMIGGSTFYINPTDMILPGGMDNSGNKTCISGINAGGDVGQGIFVLGGTFLRNVVAVFDVGAAEMRFAASA |
| Enzyme Length | 439 |
| Uniprot Accession Number | Q4WFS2 |
| Absorption | |
| Active Site | ACT_SITE 111; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094; ACT_SITE 323; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.23.- |
| Enzyme Function | FUNCTION: Probable aspartic-type endopeptidase which contributes to virulence. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Domain (1); Glycosylation (10); Region (1); Signal peptide (1) |
| Keywords | Aspartyl protease;Glycoprotein;Hydrolase;Protease;Reference proteome;Secreted;Signal;Virulence |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..20; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 46,364 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |