| IED ID | IndEnz0002012394 |
| Enzyme Type ID | protease012394 |
| Protein Name |
26S proteasome non-ATPase regulatory subunit 12 homolog A 26S proteasome regulatory subunit RPN5a AtRPN5a 26S proteasome regulatory subunit p55 homolog A Protein EMBRYO DEFECTIVE 2107 Protein MARIPOSA |
| Gene Name | RPN5A EMB2107 MSA At5g09900 MYH9.11 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
| Enzyme Sequence | MGDSGKLEATIDRLLNEEKQMRLAENVAGTRKAATEILQLCFDAKDWKLLNEQILNLSKKRGQLKQAVQSMVQQAMQYIDQTPDIETRIELIKTLNNVSAGKIYVEIERARLTKKLAKIKEEQGQIAEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDRQDFVRAQILSRKINPRVFDADTKKDKKKPKEGDNMVEEAPADIPTLLELKRIYYELMIRYYSHNNEYIEICRSYKAIYDIPSVKETPEQWIPVLRKICWFLVLAPHDPMQSSLLNATLEDKNLSEIPDFKMLLKQVVTMEVIQWTSLWNKYKDEFEKEKSMIGGSLGDKAGEDLKLRIIEHNILVVSKYYARITLKRLAELLCLSMEEAEKHLSEMVVSKALIAKIDRPSGIVCFQIAKDSNEILNSWAGNLEKLLDLVEKSCHQIHKETMVHKAALRP |
| Enzyme Length | 442 |
| Uniprot Accession Number | Q9FIB6 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Required for gametogenesis and sporophyte development. Acts redundantly with RPN5B. {ECO:0000269|PubMed:19252082}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Coiled coil (1); Domain (1); Initiator methionine (1) |
| Keywords | Alternative splicing;Coiled coil;Cytoplasm;Nucleus;Proteasome;Reference proteome |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:19252082}. Nucleus {ECO:0000269|PubMed:19252082}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 20706207; |
| Motif | |
| Gene Encoded By | |
| Mass | 50,837 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |