Detail Information for IndEnz0002012423
IED ID IndEnz0002012423
Enzyme Type ID protease012423
Protein Name Early 35 kDa protein
Apoptosis-preventing protein
p35
Gene Name P35
Organism Bombyx mori nuclear polyhedrosis virus (BmNPV)
Taxonomic Lineage Viruses Naldaviricetes Lefavirales Baculoviridae Alphabaculovirus Bombyx mori nuclear polyhedrosis virus (BmNPV)
Enzyme Sequence MCVIFPVEIDVSQTVIRDCHVDEQTRELVYINKIMNTQLTKPVLMMFNISGPIRSVTRKNNDLRDRIKSKVDEQFDQLEREYSDKIDGFHDNIQYFKDEHYSVSCQNGSVLKSKFAKILKSHDYTDKKSIETYEKYCLPQLVDKHNDCYVAVCVLKPGFENGSNQVLSFEYNPIGNKVIVPFAHEINDTGLYEYDVLAYVDSVEFDGKQFEEFVQKLILPSSFNDSEKVLYYNEASKNKNMIYKALEFTTESSWVKSNKFNWKIFCNGFIYDKKSKALYVKLHNVTSTLNKNVILDMIK
Enzyme Length 299
Uniprot Accession Number P31354
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Blocks the insect or worm host cells apoptotic response initiated by the viral infection. Confers protection from cell death in mammalian cells. Acts by blocking the activity of members of the caspase family of proteases.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1)
Keywords Apoptosis;Early protein;Host-virus interaction;Inhibition of host caspases by virus;Modulation of host cell apoptosis by virus;Protease inhibitor;Thiol protease inhibitor
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 34,912
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda