Detail Information for IndEnz0002012477
IED ID IndEnz0002012477
Enzyme Type ID protease012477
Protein Name Tricorn protease-interacting factor F3
EC 3.4.11.-
Gene Name trf3 TV0814 TVG0817891
Organism Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)
Taxonomic Lineage cellular organisms Archaea Candidatus Thermoplasmatota Thermoplasmata Thermoplasmatales Thermoplasmataceae Thermoplasma Thermoplasma volcanium Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)
Enzyme Sequence MDISEYDLTLDLDLQSKTFHGTETISASSGDFVLDAVGFNIEWIKVNGSDAKFEYDGNLLKINGLETAQKVEISYSGKISDSLSGIYFAGRESNGMVTTHFEATDARRMFPCIDHPAYKAVFSITLVIDKDYDAISNMPIKKVETSDRKIVEFEKTPRMSTYLLYIGVGKFKYASERYKDREIILASLKDIKSKYPIDIAKRSIEFYEGYFGIPYALPKMHLISVPEFGAGAMENWGAITFREIYLDIADNSAASTLRLSANVIAHEIAHQWFGDLVTMKWWNDLWLNESFATFMSYKTMDTIHPEWQFWGDFFVSRTSGALRSDSLKNTHPIEVDVKDPDEISQIFDEISYGKGASILRMIEDYVGAEDFRKGISKYLKEHAYGNAEGSDLWNAIETESGKPVNRIMEAWITKAGYPILKVSQDKTGIKVMQSRFFLGGGESTDRWPVPVKMRLNNGISQMLLEEESTVITDKDVIKLNADNLGFYRVNYDDETFSKIIENMDKLTPLDRVGLVDDLFAFLMAGVITPDTYKNRIKSFFNDKDANVISNIVNQFEYLRIITHYFDADAREFLGTAIRYLESADDENLKIAYGKASRLLALLDEAYCETLAPRFSNFEQQTPELKSAIATAYALSTGDVKGMVEKYRSLDRDEDKVKIISGFGKLKSSTDLSVVSGMIEKGEIKKQDMLSFYLSALETMAGREYIYSNLENIVKNVIRYFTGNRTASRTVEQILPVIGLTHPDAASIIERIGSKNTTMGLAKGKELLEVNRSLLERIGH
Enzyme Length 779
Uniprot Accession Number Q97AJ6
Absorption
Active Site ACT_SITE 267; /note=Proton acceptor; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095
Activity Regulation
Binding Site BINDING 102; /note=Substrate; /evidence=ECO:0000250
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.11.-
Enzyme Function FUNCTION: Proteases F1, F2 and F3 degrade oligopeptides produced by Tricorn (themselves probably produced by the proteasome), yielding free amino acids. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Binding site (1); Chain (1); Metal binding (3); Region (1); Site (1)
Keywords Aminopeptidase;Cytoplasm;Hydrolase;Metal-binding;Metalloprotease;Protease;Zinc
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 88,069
Kinetics
Metal Binding METAL 266; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095; METAL 270; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095; METAL 289; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095
Rhea ID
Cross Reference Brenda