| IED ID | IndEnz0002012613 |
| Enzyme Type ID | protease012613 |
| Protein Name |
Probable aspartic-type endopeptidase TRV_06366 EC 3.4.23.- |
| Gene Name | TRV_06366 |
| Organism | Trichophyton verrucosum (strain HKI 0517) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Arthrodermataceae (dermatophytes) Trichophyton Trichophyton verrucosum (Cattle ringworm fungus) Trichophyton verrucosum (strain HKI 0517) |
| Enzyme Sequence | MHVSTLLVAVLLPLALSKPTPRKKTSSFKVHLARRGETEYYRDGPTDLQRAYAKYGIPTTHEMEGYHPQPISKLPGNSKATAGSGKEGVESQDEKGEVVNNPTDHDIQFLSPVTIGGQPFIMNFDTGSSDTWVMNTQMTDEEAKKDHHLYDPSKSKTASKLVDQNFDIKYGDKTHASGPVYSDVMDIGGATVRNQAIGLPSKVAASLAEDKTSDGLVGLAMTKLNTIRPVKQKTFFENLAEDLDEPVFTAQLRHGKMGSYEFGAIDKSKYHGDLIKVPVINENGFWEIPCSLYSVGKLDKIQTIQNGTGTAILDTGTTLLVLDEKIVKAYYAQVPGARYDPTRFAGWVYPCNSPMPSLFLAVGTDHMAIIPSSLLTFQSYGPGPDGVETCYGGLQSNNAGGIQILGDVFFKALFVVFDQRGPSISLAPHA |
| Enzyme Length | 430 |
| Uniprot Accession Number | D4DGR1 |
| Absorption | |
| Active Site | ACT_SITE 125; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094; ACT_SITE 314; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.23.- |
| Enzyme Function | FUNCTION: Probable secreted aspartic-type endopeptidase which contributes to virulence. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Domain (1); Glycosylation (1); Propeptide (1); Region (1); Signal peptide (1) |
| Keywords | Aspartyl protease;Glycoprotein;Hydrolase;Protease;Secreted;Signal;Virulence;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..17; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 46,757 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |