| IED ID | IndEnz0002012665 |
| Enzyme Type ID | protease012665 |
| Protein Name |
Kunitz-type serine protease inhibitor NACI Naja atra chymotrypsin inhibitor ACI NA-CI |
| Gene Name | |
| Organism | Naja atra (Chinese cobra) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Sauropsida Sauria (diapsids) Lepidosauria (lepidosaurs) Squamata (squamates) Bifurcata (split-tongued squamates) Unidentata Episquamata Toxicofera Serpentes (snakes) Colubroidea Elapidae Elapinae Naja Naja atra (Chinese cobra) |
| Enzyme Sequence | MSSGGLLLLLGLLTLWAELTPVSGRPRFCELAPSAGSCFAFVPSYYYNQYSNTCHSFTYSGCGGNANRFRTIDECNRTCVG |
| Enzyme Length | 81 |
| Uniprot Accession Number | Q5ZPJ7 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Serine protease inhibitor that inhibits chymotrypsin (Ki=25 nM). {ECO:0000269|PubMed:14990218, ECO:0000269|PubMed:15698956}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Beta strand (3); Chain (1); Disulfide bond (3); Domain (1); Glycosylation (1); Helix (4); Signal peptide (1); Site (1) |
| Keywords | 3D-structure;Direct protein sequencing;Disulfide bond;Glycoprotein;Protease inhibitor;Secreted;Serine protease inhibitor;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..24; /evidence=ECO:0000250 |
| Structure 3D | NMR spectroscopy (1) |
| Cross Reference PDB | 2M99; |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 8,815 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |