Detail Information for IndEnz0002012697
IED ID IndEnz0002012697
Enzyme Type ID protease012697
Protein Name Serine protease inhibitor Kazal-type 4
MPGC60 protein
Peptide PEC-60 homolog
Gene Name Spink4 Mpgc60
Organism Mus musculus (Mouse)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Glires (Rodents and rabbits) Rodentia Myomorpha (mice and others) Muroidea Muridae Murinae Mus Mus Mus musculus (Mouse)
Enzyme Sequence MAMHLWLVTLTLVPLLGMDRELMVSAGSLVFPRMPFCEHMAELPNCPQTPNLICGTDGLTYENECHLCLTRMKTMKDIQIMKDGQC
Enzyme Length 86
Uniprot Accession Number O35679
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Disulfide bond (3); Domain (1); Sequence conflict (1); Signal peptide (1); Site (1)
Keywords Disulfide bond;Protease inhibitor;Reference proteome;Secreted;Serine protease inhibitor;Signal
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..26; /evidence=ECO:0000250
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 14610273; 16602821; 17062627; 18554416; 19549527; 20562862; 21267068;
Motif
Gene Encoded By
Mass 9,729
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda