| IED ID |
IndEnz0002012773 |
| Enzyme Type ID |
protease012773 |
| Protein Name |
pH-response transcription factor pacC/RIM101
|
| Gene Name |
RIM101 CD36_13310 |
| Organism |
Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841) (Yeast) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Fungi
Dikarya
Ascomycota
saccharomyceta
Saccharomycotina (true yeasts)
Saccharomycetes
Saccharomycetales
Debaryomycetaceae
Candida/Lodderomyces clade
Candida
Candida dubliniensis (Yeast)
Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841) (Yeast)
|
| Enzyme Sequence |
MNYNIHPVTYLNADSSNTGTAETTTQHHHGSKKSPSSDIDVDNATSPSSFTSSQSPHINAMGNSPHSSFTSQSAANSPITDAKQHLVKTTTNEHKPAAFTPSVGQQPASQTNTTAPQSYTQPAQQLPTQLHPSLNQVYNNQPSYYLHQPAYGYQQQPLHQEYNQQPQQYHDHHGYYANNNNIPSINELNQKPPAPVKPFKKTYKKIRDEDLKGPFKCLWSNCNIIFETPEILYDHLCDDHVGRKSSNNLSLTCLWENCGTTTVKRDHITSHLRVHVPLKPFHCDLCTKSFKRPQDLKKHSKTHAEDHPKKLKKAQRELMKQQQKEAKQQQKLANKRANATTASDLQLNYYSGNPGDGLYDEASRKRRYENNSQHNMYVVNSILNDFNFQQMAQPPQQPGAVSTAVSSEFTTKRMKSGSEYNIDVFNKLNHLDDHLHHHHPQQNPQQYGGNIYEAEKFFNSLSNSIDMQYQNMSSQYQQQNPGVASFAQQKPAQQTNGQLYPSLPTIGNGSYTTSSSSSHKEGLVNNHNGYLPSYPQINRSLPYSGVAQQPPSALEFGGVSTYQKSAQSYEDSSESSDDDDDDEDDDDYSTSSEEELDALFDKLNIVDKNVEEVTIDGFNLKDVAKHRDMIHSVLVYLRKQIEQQEKEKSQEQKDDVNQLYPTITAF |
| Enzyme Length |
666 |
| Uniprot Accession Number |
Q873Y3 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including RIM101 itself) and represses transcription of acid-expressed genes (By similarity). {ECO:0000250}. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Coiled coil (1); Compositional bias (5); Motif (3); Region (5); Sequence conflict (2); Zinc finger (3) |
| Keywords |
Activator;Coiled coil;Cytoplasm;DNA-binding;Metal-binding;Nucleus;Repeat;Repressor;Transcription;Transcription regulation;Zinc;Zinc-finger |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
| Modified Residue |
|
| Post Translational Modification |
PTM: Activated by C-terminal proteolytic cleavage by signaling protease at neutral to alkaline ambient pH. {ECO:0000250}. |
| Signal Peptide |
|
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
MOTIF 500..503; /note=YPX[LI] motif 1; MOTIF 534..537; /note=YPX[LI] motif 2; MOTIF 660..663; /note=YPX[LI] motif 3 |
| Gene Encoded By |
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| Mass |
75,299 |
| Kinetics |
|
| Metal Binding |
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| Rhea ID |
|
| Cross Reference Brenda |
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