| IED ID |
IndEnz0002012775 |
| Enzyme Type ID |
protease012775 |
| Protein Name |
pH-response transcription factor pacC/RIM101
|
| Gene Name |
pacC AO090003000758 |
| Organism |
Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Fungi
Dikarya
Ascomycota
saccharomyceta
Pezizomycotina
leotiomyceta
Eurotiomycetes
Eurotiomycetidae
Eurotiales (green and blue molds)
Aspergillaceae
Aspergillus
Aspergillus subgen. Circumdati
Aspergillus oryzae (Yellow koji mold)
Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
|
| Enzyme Sequence |
MSEPQDTTSPSTAAAPIAASTSHEQPQTQSPPQVSATTTSSVTATAAAATAAVASPPVNGAARPTEELSCLWQGCSEKCPTPESLYEHVCERHVGRKSTNNLNLTCQWGSCRTTTVKRDHITSHIRVHVPLKPHKCDFCGKAFKRPQDLKKHVKTHADDSVLVRSPEPGSRNPDIMFGGNPAKGYATATHYFEPALNPVPSQGYAHGAPQYYQSHHPPQPANPSYGNVYYALNHGHEAGHASYESKKRGYDALNEFFGDLKRRQFDPNSYAAVGQRLLGLQSLSLPILSGGPLPEYQPMPAPVAVGGGGYSPGGHPPAPAYHLPPMSNVRTKNDLINIDQFLQQMQDTIYENDDNVAAAGVAQPGAHYVHGGMSYRTTHSPPSQLPPSHATATTSAGPIMANPATHSPTGTPALTPPSSAQSYTSGRSPISLPSTSRVSPPHHEGGSSMYPRLPSATMSDSMAAGYPTTSSAAPPSTLGGIFDHDDRRRYTGGTLQRARPEERHLPEPMDLSHDNKDDGERTPPAKPRQAPSSPGRISASLIDPALSGSANEAETMRTAQAATEVAERSDVQWVEKVRLIEYLRNYIASRLERGEYDGDSGMTRESRTPEAGPDGHMEGVETEPVSHPAKCESPVKPEAGGDTVMYPTLRGVDEDGDSKMPN |
| Enzyme Length |
662 |
| Uniprot Accession Number |
Q9HFB3 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
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| Enzyme Function |
FUNCTION: Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid-expressed genes (By similarity). {ECO:0000250}. |
| Temperature Dependency |
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| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Compositional bias (4); Motif (2); Region (3); Sequence conflict (1); Zinc finger (3) |
| Keywords |
Activator;Cytoplasm;DNA-binding;Metal-binding;Nucleus;Reference proteome;Repeat;Repressor;Transcription;Transcription regulation;Zinc;Zinc-finger |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
| Modified Residue |
|
| Post Translational Modification |
PTM: Activated by C-terminal proteolytic cleavage by signaling protease (probably palB/RIM13) at neutral to alkaline ambient pH. {ECO:0000250}. |
| Signal Peptide |
|
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
MOTIF 450..453; /note=YPX[LI] motif 1; MOTIF 646..649; /note=YPX[LI] motif 2 |
| Gene Encoded By |
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| Mass |
70,801 |
| Kinetics |
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| Metal Binding |
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| Rhea ID |
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| Cross Reference Brenda |
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