| IED ID | IndEnz0002012816 |
| Enzyme Type ID | protease012816 |
| Protein Name |
Tick anticoagulant peptide TAP |
| Gene Name | |
| Organism | Ornithodoros moubata (Soft tick) (Argasid tick) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Chelicerata Arachnida Acari Parasitiformes Ixodida (ticks) Ixodoidea Argasidae (softbacked ticks) Ornithodoros (relapsing fever ticks) Ornithodoros moubata (Soft tick) (Argasid tick) |
| Enzyme Sequence | YNRLCIKPRDWIDECDSNEGGERAYFRNGKGGCDSFWICPEDHTGADYYSSYRDCFNACI |
| Enzyme Length | 60 |
| Uniprot Accession Number | P17726 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: TAP is a slow, tight-binding inhibitor of blood coagulation, specific for factor Xa. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Beta strand (2); Chain (1); Disulfide bond (3); Domain (1); Helix (3); Turn (2) |
| Keywords | 3D-structure;Direct protein sequencing;Disulfide bond;Protease inhibitor;Serine protease inhibitor |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | NMR spectroscopy (2); X-ray crystallography (2) |
| Cross Reference PDB | 1D0D; 1KIG; 1TAP; 1TCP; |
| Mapped Pubmed ID | 10716178; 9761680; |
| Motif | |
| Gene Encoded By | |
| Mass | 6,985 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |