| IED ID | IndEnz0002012886 |
| Enzyme Type ID | protease012886 |
| Protein Name |
Trypsin EC 3.4.21.4 SET |
| Gene Name | |
| Organism | Saccharopolyspora erythraea (Streptomyces erythraeus) |
| Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Actinobacteria Actinomycetia (high G+C Gram-positive bacteria) Pseudonocardiales Pseudonocardiaceae Saccharopolyspora Saccharopolyspora erythraea (Streptomyces erythraeus) |
| Enzyme Sequence | IVGGEDANVQDHPFTVALVTPDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSGRTVMSSNIGTVSKVTNVWVHPEYQDAAKGFDVSVLTLEAPVKEAPIELAKADDAGYAPDTAATILGWGNTSEGGQQADHLQKATVPVNSDDTCKQAYGEYTPNAMVCAGVPEGGVDTCQGDSGGPMVVNNKLIGVTSWGEGCARPGKPGVYARVGAYYDVLMEQINAGAV |
| Enzyme Length | 227 |
| Uniprot Accession Number | P24664 |
| Absorption | |
| Active Site | ACT_SITE 42; /note=Charge relay system; ACT_SITE 88; /note=Charge relay system; ACT_SITE 179; /note=Charge relay system |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.; EC=3.4.21.4; |
| DNA Binding | |
| EC Number | 3.4.21.4 |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Beta strand (13); Chain (1); Disulfide bond (3); Domain (1); Helix (8); Site (1); Turn (1) |
| Keywords | 3D-structure;Direct protein sequencing;Disulfide bond;Hydrolase;Protease;Serine protease |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | X-ray crystallography (2) |
| Cross Reference PDB | 4M7G; 5DK1; |
| Mapped Pubmed ID | 22115549; 24598752; |
| Motif | |
| Gene Encoded By | |
| Mass | 23,308 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda | 3.4.21.4; |