Detail Information for IndEnz0002012900
IED ID IndEnz0002012900
Enzyme Type ID protease012900
Protein Name NADH-ubiquinone oxidoreductase 40 kDa subunit, mitochondrial
Complex I-40kD
CI-40kD
Gene Name nuo40 NCU02373
Organism Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta sordariomyceta Sordariomycetes Sordariomycetidae Sordariales Sordariaceae Neurospora Neurospora crassa Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Enzyme Sequence MAPLTAAMRSTPRIIVSNAFGFQRRAISDVTITRTGKPIIRNQGGRSSLGGHTATVFGATGQLGRYIVNRLARQGCTVVIPFRDEYNKRHLKVTGDLGKVVMIEFDLRNTQSIEESVRHSDVVYNLIGRDYPTKNFSFEDVHIEGAERIAEAVAKYDVDRFIHVSSYNADPNSECEFFATKARGEQVVRSIFPETTIVRPAPMFGFEDRLLHKLASVKNILTSNGMQEKYNPVHVIDVGQALEQMLWDDNTASETFELYGPKTYTTAEISEMVDREIYKRRRHVNVPKKILKPIAGVLNKALWWPIMSADEIEREFHDQVIDPEAKTFKDLGIEPADIANFTYHYLQSYRSNAYYDLPPATEKERREDREYIHML
Enzyme Length 375
Uniprot Accession Number P25284
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Sequence conflict (2); Transit peptide (1)
Keywords Direct protein sequencing;Electron transport;FAD;Flavoprotein;Mitochondrion;Reference proteome;Respiratory chain;Transit peptide;Transport
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Mitochondrion matrix.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 42,870
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda