IED ID |
IndEnz0002012914 |
Enzyme Type ID |
protease012914 |
Protein Name |
pH-response regulator protein palA/prr-1
|
Gene Name |
prr-1 rim20 NCU05876 |
Organism |
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) |
Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Fungi
Dikarya
Ascomycota
saccharomyceta
Pezizomycotina
leotiomyceta
sordariomyceta
Sordariomycetes
Sordariomycetidae
Sordariales
Sordariaceae
Neurospora
Neurospora crassa
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
|
Enzyme Sequence |
MTTTHVLSLPFRKSTQLSLSRAIQQYISAKYDQHPDMFRHDLDTIDALRRDAINVREAHPSGIRKLQMYAAQLVWIGGKFPIDVGADFTWYPALGYHTEHPLVQNNLKYELMNVLYNLAALYSQLAVASNRNSTEGLKTAASWFSHSAGVLTHIKTQVLPELRMPSPPDDMDETTLESLIQLFLAEAQECYWQKAVMDGYKDASIAKLAARVSDLYNEAGEAAMRSEAISSAWIHHMSAKHHHFAAAAQFRAASDCLERKKYGEEIARLRDAVACVNEGLKETRGGYLSKAVVEDLQGLKRRLEEDLKRAEIDNDRVYLHIVPPKTELKRLDRANMAVARVPPQVAKPYEFLGDPSAEFGPALFTKLVPFAVHVAVSIYEERRDRLVNNSIISELESMTSQLHEILSSLNLPGSLQALEKPLGLPGTLVQHADEIRQADALYRLQQGLTDIDKLCSSDLAIFEEGRSLLLAEEEEDSRLRLKYGTERWNRPQSRQDPSPNGGTKLWRQAQDIEGYFGSSTASDQVVREKFNAVRDTLTILAGSDRSIMDFIPNSRRTDIPESLKPALGRLRSAYNDVQRLESRRRKRVESLRARSRADDIKPDILVEAARLERAYPTTAIATAHFEDFFEKRLDRLYESELEAVERDKQEQEKIVQEVKRANKEFEAQKRQVDRAGGGNREREEALQKLDAAYYKYKEIVSNVEVGRKFYNDLSQIVEQWRGLVRGWVSERRRDARSLEEEINMPPLSSLNMHQSSFSYQQQQHHQQPPPPPPQIPFPEPIQPHQPIVEQAHIQSWADNVPQQQPKPVAPGAWAPNMGIKFGSPVAQGQQHQQEQGQPGPVNATWDPSQGIRFG |
Enzyme Length |
854 |
Uniprot Accession Number |
Q7S532 |
Absorption |
|
Active Site |
|
Activity Regulation |
|
Binding Site |
|
Calcium Binding |
|
catalytic Activity |
|
DNA Binding |
|
EC Number |
|
Enzyme Function |
FUNCTION: Required for the proteolytic cleavage of the transcription factor pacc-1 in response to alkaline ambient pH. May act as a scaffold protein that recruits the calpain-like protease palB/cpr-8 via snf7/vps-3 to its substrate pacc-1 (By similarity). {ECO:0000250}. |
Temperature Dependency |
|
PH Dependency |
|
Pathway |
|
nucleotide Binding |
|
Features |
Chain (1); Coiled coil (1); Compositional bias (3); Domain (1); Region (2) |
Keywords |
Coiled coil;Reference proteome |
Interact With |
|
Induction |
|
Subcellular Location |
|
Modified Residue |
|
Post Translational Modification |
|
Signal Peptide |
|
Structure 3D |
|
Cross Reference PDB |
- |
Mapped Pubmed ID |
- |
Motif |
|
Gene Encoded By |
|
Mass |
96,904 |
Kinetics |
|
Metal Binding |
|
Rhea ID |
|
Cross Reference Brenda |
|