| IED ID | IndEnz0002012940 |
| Enzyme Type ID | protease012940 |
| Protein Name |
26S proteasome regulatory subunit 6A homolog B 26S proteasome AAA-ATPase subunit RPT5b Proteasome 26S subunit 6A homolog B Regulatory particle triple-A ATPase subunit 5b Tat-binding protein 1 homolog B TBP-1 homolog B |
| Gene Name | RPT5B TBP1 At1g09100 F7G19.2 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
| Enzyme Sequence | MATAMAEDTSFEGDQLASMTTDDIGRASRLLANEIRILKEESQRTNLDLESVKEKIKENQEKIKLNKQLPYLVGNIVEILEMSPEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLPVVGLVDPDTLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEAIVLPMTHKEQFEKLGIRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGDGAKLVRDAFLLAKEKSPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSSDDRIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEARGRILQIHSRKMNVNADVNFEELARSTDDFNGAQLKAVCVEAGMLALRRDATEVNHEDFNEGIIQVQAKKKASLNYYA |
| Enzyme Length | 423 |
| Uniprot Accession Number | O04019 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. {ECO:0000269|PubMed:17081979}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | NP_BIND 211..218; /note=ATP; /evidence=ECO:0000255 |
| Features | Chain (1); Cross-link (3); Erroneous initiation (1); Modified residue (1); Nucleotide binding (1) |
| Keywords | ATP-binding;Cytoplasm;Isopeptide bond;Nucleotide-binding;Nucleus;Phosphoprotein;Proteasome;Reference proteome;Ubl conjugation |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
| Modified Residue | MOD_RES 18; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:Q9SEI4 |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 11782485; 12368493; 15449379; 17317660; 17432890; 17825468; 18650403; 19704756; 20118269; 20226671; 20682047; 20706207; 20736450; 21784786; 21798944; |
| Motif | |
| Gene Encoded By | |
| Mass | 47,038 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |