Detail Information for IndEnz0002012942
IED ID IndEnz0002012942
Enzyme Type ID protease012942
Protein Name 26S proteasome non-ATPase regulatory subunit 12 homolog B
26S proteasome regulatory subunit RPN5b
AtRPN5b
26S proteasome regulatory subunit p55 homolog B
Gene Name RPN5B At5g64760 MVP7.9
Organism Arabidopsis thaliana (Mouse-ear cress)
Taxonomic Lineage cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress)
Enzyme Sequence MEESRQLESSIDRLLNEEKQMRLAENVAGTRKAATEILKLCFEAKDWKLLNEQILNLSKKRGQLKQAVQSMVQQAMQYIDQTLDIETRIELIKTLNNVAAGKIYVEIERARLTKMLAKIKEEQGLIAEAADLMQEVAVETFGAMAKTEKIAFILEQVRLCLDQKDFVRAQILSRKINPRVFDADTTKEKKKPKEGENMVEEAPADIPTLLVLKRIYYELMIRYYSHNNEYIEICRSYKAIYDIPSVKENPEQWIPVLRKICWFLALAPHDPMQSSLLNATLEDKKLSEIPDFKMLLKQIVTMEVIQWTSLWNKYKDEFENEKNMIGGSLGDKAGEDLKLRIIEHNILVVSKYYSRITFKRLAELLCLTTEEAEKHLSEMVVSKALIAKIDRPSGIICFQIVKDSNEILNSWATNLEKLLDLVEKSCHQIHKETMVHKVALRA
Enzyme Length 442
Uniprot Accession Number Q8VWK0
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins (By similarity). Acts redundantly with RPN5A. {ECO:0000250, ECO:0000269|PubMed:19252082}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Coiled coil (1); Domain (1); Erroneous gene model prediction (1)
Keywords Alternative splicing;Coiled coil;Cytoplasm;Nucleus;Proteasome;Reference proteome
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:19252082}. Nucleus {ECO:0000269|PubMed:19252082}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 10363660; 11742986; 17411438; 17825468; 28627464;
Motif
Gene Encoded By
Mass 51,118
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda