IED ID | IndEnz0002012959 |
Enzyme Type ID | protease012959 |
Protein Name |
Protein C activator EC 3.4.21.- Snake venom serine protease SVSP Fragment |
Gene Name | |
Organism | Gloydius halys (Chinese water mocassin) (Agkistrodon halys) |
Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Sauropsida Sauria (diapsids) Lepidosauria (lepidosaurs) Squamata (squamates) Bifurcata (split-tongued squamates) Unidentata Episquamata Toxicofera Serpentes (snakes) Colubroidea Viperidae Crotalinae (pit vipers) Gloydius Gloydius halys (Chinese water mocassin) (Agkistrodon halys) |
Enzyme Sequence | VVGGDECNINEHRSL |
Enzyme Length | 15 |
Uniprot Accession Number | P80899 |
Absorption | |
Active Site | |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | |
DNA Binding | |
EC Number | 3.4.21.- |
Enzyme Function | FUNCTION: Snake venom serine protease that selectively cleaves the heavy chain of protein C (PROC). This activation is thrombomodulin-independent (By similarity). {ECO:0000250}. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Chain (1); Domain (1); Non-terminal residue (1) |
Keywords | Blood coagulation cascade inhibiting toxin;Direct protein sequencing;Hemostasis impairing toxin;Hydrolase;Protease;Secreted;Serine protease;Toxin |
Interact With | |
Induction | |
Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000269|Ref.1}. |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | - |
Motif | |
Gene Encoded By | |
Mass | 1,642 |
Kinetics | |
Metal Binding | |
Rhea ID | |
Cross Reference Brenda |