| IED ID | IndEnz0002013027 |
| Enzyme Type ID | protease013027 |
| Protein Name |
Zinc metalloproteinase-disintegrin-like proatherocytin SVMP EC 3.4.24.- Fragments |
| Gene Name | |
| Organism | Proatheris superciliaris (Lowland swamp viper) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Sauropsida Sauria (diapsids) Lepidosauria (lepidosaurs) Squamata (squamates) Bifurcata (split-tongued squamates) Unidentata Episquamata Toxicofera Serpentes (snakes) Colubroidea Viperidae Viperinae (vipers) Proatheris Proatheris superciliaris (Lowland swamp viper) |
| Enzyme Sequence | GNYYGYCRVHLNTAY |
| Enzyme Length | 15 |
| Uniprot Accession Number | P85005 |
| Absorption | |
| Active Site | |
| Activity Regulation | ACTIVITY REGULATION: Inhibited by the serine protease inhibitor AEBSF. {ECO:0000269|PubMed:16112700}. |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.24.- |
| Enzyme Function | FUNCTION: Stimulates platelet aggregation through activation of PAR-1 (F2R). {ECO:0000269|PubMed:16112700}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Non-adjacent residues (1); Non-terminal residue (1) |
| Keywords | Direct protein sequencing;Hemostasis impairing toxin;Hydrolase;Metal-binding;Metalloprotease;Platelet aggregation activating toxin;Protease;Secreted;Toxin;Zinc |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:16112700}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 1,794 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |