| IED ID | IndEnz0002013028 |
| Enzyme Type ID | protease013028 |
| Protein Name |
Kunitz-type serine protease inhibitor homolog beta-bungarotoxin B5-B chain Beta-bungarotoxin B5 chain |
| Gene Name | |
| Organism | Bungarus multicinctus (Many-banded krait) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Sauropsida Sauria (diapsids) Lepidosauria (lepidosaurs) Squamata (squamates) Bifurcata (split-tongued squamates) Unidentata Episquamata Toxicofera Serpentes (snakes) Colubroidea Elapidae Bungarinae Bungarus Bungarus multicinctus (Many-banded krait) |
| Enzyme Sequence | RQRHPDCDKPPDTKRCTGHNPAFYYNPRRKNCERFSYGGCGGNGNHFKTKQLCHCHCHEND |
| Enzyme Length | 61 |
| Uniprot Accession Number | Q0PL65 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Beta-bungarotoxins are presynaptic neurotoxins of the venom. The B chain is homologous to venom basic protease inhibitors but has no protease inhibitor activity and blocks voltage-gated potassium channels (Kv) (By similarity). {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Disulfide bond (4); Domain (1) |
| Keywords | Disulfide bond;Ion channel impairing toxin;Neurotoxin;Potassium channel impairing toxin;Presynaptic neurotoxin;Secreted;Toxin;Voltage-gated potassium channel impairing toxin |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 7,134 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |