| IED ID | IndEnz0002013228 |
| Enzyme Type ID | protease013228 |
| Protein Name |
ATP-dependent zinc metalloprotease YME1 homolog EC 3.4.24.- |
| Gene Name | |
| Organism | Schistosoma mansoni (Blood fluke) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Spiralia Lophotrochozoa Platyhelminthes Trematoda Digenea (flukes) Strigeidida Schistosomatoidea Schistosomatidae (blood flukes) Schistosoma Schistosoma mansoni (Blood fluke) |
| Enzyme Sequence | MIVSPCCRIIRTCCVSNRGTFHSRLAALYPSYIKIPNNHARIFVTKSRKINRPSSSFIIDTKEARQRNSDSSTVSSDLDEILKDQTPSAQLRLVDAYRRGFQSSTDSGKSSNKMQMWRTIIIKTILFGVVSCFTIVFLKKTLVGTFPKFLDQNIGSFAENTDVSFSDVQGCDEVKKELVDVVEFLRNPEKFNQIGAKLPKGVLLVGPPGVGKTLLAKAVSGEAQVPFLYASGSSFDEVLVGLGASRIRQLFTTAKQNSPCLVFIDEIDSVGGNRTFSPHHPFANQTINQLLAEMDGFQSKEGIIVLGATNQAEVLDKALLRPGRFDVQIHVSPPTYEGRIALLNLYLKKVKTGSNIDIEKLAHGTVGYTGADIQNLVNQAAIAAALRNDPFVEMHHLWDARDRLIMGPAKRRPLDDQTNRVSAFHEAGHALVALLTADSIPLHKVTIIPRGEAGGLTSFLQEKDISFMTRAQLLAQLDVLMGGRVGEELVFGADKVTNGAADDFRKATILAQNMVKRFGFSSKIGPRVIPDTQDEQLGEATRDLIDKEVDQLLNDSLTRVRTLLSSQSKQHKLLAEALLHFETLTKDEVLAVLAGKMKPPKTQSVTSKSTTLLPQLGPSTSTEIPRMIVSLIIVHVVDFISFFCPFKDTLHTYTHTHKLLFS |
| Enzyme Length | 662 |
| Uniprot Accession Number | P46508 |
| Absorption | |
| Active Site | ACT_SITE 426; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.24.- |
| Enzyme Function | FUNCTION: Putative ATP-dependent protease. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | NP_BIND 206..213; /note=ATP; /evidence=ECO:0000255 |
| Features | Active site (1); Chain (1); Metal binding (3); Nucleotide binding (1) |
| Keywords | ATP-binding;Hydrolase;Metal-binding;Metalloprotease;Nucleotide-binding;Protease;Reference proteome;Zinc |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 72,940 |
| Kinetics | |
| Metal Binding | METAL 425; /note=Zinc; catalytic; /evidence=ECO:0000250; METAL 429; /note=Zinc; catalytic; /evidence=ECO:0000250; METAL 503; /note=Zinc; catalytic; /evidence=ECO:0000250 |
| Rhea ID | |
| Cross Reference Brenda |