| IED ID | IndEnz0002013230 |
| Enzyme Type ID | protease013230 |
| Protein Name |
Inactive ubiquitin carboxyl-terminal hydrolase 54 Inactive ubiquitin-specific peptidase 54 |
| Gene Name | Usp54 |
| Organism | Rattus norvegicus (Rat) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Glires (Rodents and rabbits) Rodentia Myomorpha (mice and others) Muroidea Muridae Murinae Rattus Rattus norvegicus (Rat) |
| Enzyme Sequence | MSWKRNYFSGGRGSVQGMFAPRSSMSIAPSKGLSNEPGQNSCFLNSALQVLWHLDIFRRSFRQLTSHKCMGDSCIFCALKGIFKQFQCSSEKVLPSDTLRSALAKTFQDEQRFQLGIMDDAAECFENLLMRIHFHIADETKEDICTAPHCISHQKFAMTLFEQCVCTSCGATSDPLPFIQMVHYISTTSLCNQAICMLEKREKPSPGMFGELLQNASTMGDLRDCPSNCGERIRIRRVLMNAPQIITIGLVWDSDHSDLAEDVIHSLGTCLKLGDLFFRVTDDRAKQSELYLVGMICYYGKHYSTFFFQTKIRKWMYFDDAHVKEIGPKWKDVVTKCIKGHYQPLLLLYADPQGTPVSAQDLPPHAQLLSHTKTCYDSEDSGHLTDSECNQKHTTKKGPLVERRRGSGRIRRKADAPQASGYHSEGETLKEKQAPRNASKSSSTSRLKDFKETVSNMIHSRPSLASQTNAASPCVGRAGDQPDKIPARNLPLHSRGWETESTSSEARSSSSSKYRPTWRPKRESLNIDSIFSKDKRKHCGYTQLKTFPEDAAKEFAQDEVSNPVANDIKDGGPSSQHKLWGTARPGSHLLEQHPRLIQRMESGYESSERNSSSPVSLDAAPPECLNVYRDQSTKRAVGFVPSWRHIPKSHSSSILEVDSTAPVTGWTETQPFSDGEITSKSELDELQEEVARRAQEQELRKKREKELEAAKGFNPHPSRYMDLDELQNQGRSDGFERSLQEANSVFEESLHLEQEGDCAAALALCNEAISKLRLTLHDASSSTHSRALVDKKLQISIRKARSLQDRMQQQPPSQQPVQPSASLPSQGGGLPQPTSEQSVPLQVLLSQQTQLEPCKDSELGATSPFFHSPASCPEPHSSLVSPSPAQSVSQHSPPGTSALKLLKSFEVDIVNHSAFHRQDLPKATGRTEMNSQHECLPFDALEDRLQGHREDNSCCSKFPPQEGRDTTQDQLLEGRKTPVDISMGMPWSHSAGGATSERVMHSLNSPSSPSAQPAVPPYGACHPIMSAAASPVLHAADPMQKLNQHLQAQSLQTSLASKVVRGSEEPYRPEFPSTKGLVRSLAEQFQKIRNTSTRDVIGSQDRSLPNGLRKSSSPSDFMLPLSQGPEKEHCRWVNQPPSPDGRERQPCWEEPAGHPSVSIDSGLPNGEASRRRQPRLAEADIYQGKLPQVTDTRPTELGSSVSLGTSLPLDSWVNVTRLCDSQVKHRAPGLGVKSSSHDSRTCVTYPERNPILLHPHWNQDTEQETSELESLYQASLQASSHTGYSDWRSQDVAWQPLSLTGSADGMGRRLHSAPGLDLSKTPTAEMERILYEPSTVPVSQDSSNVRKKTLETGHHCSSSSSLPVIHDPPVFLLDPKLYPPQPQFLSPDVLMPSMAGEPYRSPGTSRSVQQFLAMCDRDETPQGVKYTGRTLNYRSLPHRSRTDASWGPGTETNQHIGARVLTAPACKPQLTYTATLPERHQGLQVPHAQSWGNLFHLPSHPSAVHPGSPPSSSLHVLHRSSWNSGSVLGSRTPGPRRIDVPPDDDGRQSQYPSQYRHRSAGEERVRFALSNTAGTEQSRVRLLQHSRW |
| Enzyme Length | 1588 |
| Uniprot Accession Number | Q6IE24 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Has no peptidase activity. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Alternative sequence (2); Chain (1); Coiled coil (1); Compositional bias (6); Domain (1); Modified residue (6); Region (8); Sequence conflict (1) |
| Keywords | Alternative splicing;Coiled coil;Methylation;Phosphoprotein;Reference proteome |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | MOD_RES 12; /note=Omega-N-methylarginine; /evidence=ECO:0000250|UniProtKB:Q8BL06; MOD_RES 424; /note=Phosphoserine; /evidence=ECO:0007744|PubMed:22673903; MOD_RES 574; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:Q70EL1; MOD_RES 613; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:Q70EL1; MOD_RES 616; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:Q8BL06; MOD_RES 1138; /note=Phosphoserine; /evidence=ECO:0007744|PubMed:22673903 |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 176,155 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |