| IED ID | IndEnz0002013312 |
| Enzyme Type ID | protease013312 |
| Protein Name |
Putative carboxypeptidase suro-1 EC 3.4.17.- Suppressor of roller 1 |
| Gene Name | suro-1 R11A5.7 |
| Organism | Caenorhabditis elegans |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Nematoda (roundworms) Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis Caenorhabditis elegans |
| Enzyme Sequence | MRYLCKSILLAVHTILLVGSVCCSTDVHNTDDKYALIHVSAHDEQSLHLIKQLQLNDFKYDLDFWKSPSSISDKADIMVKRGKSERMLRQILSFANVTVSMSVPDVEKLIMRNEGTTSKSHLGFGSLSKWLHDDPILDSEPDLDLTKVGALKKAKYPFGDYASYADMVKYMRTIEFYYPRIAKIVRIGATHEGKPIEGLKIGARSSHKKRAVWVDGNIHAREWASSHTALYFINQLVSEYGKDAQITNYVDTLDFYIVPCLNPDGYEYTRTSPIPTVRLWRKNRSPELCRPSLWGGEKCCRGVDLNRNFRFHWAERGSSYEPCSNIYHGEEVFSEPETRAVRNFLATPEMKDRVDAFVTLHSYAQLWIYPYSHEEQNYPEDIGELRKTARKAINRLSRVYGTNYRMGTGADTLSPAAGGSDDWAKSALNVKYVYLIELRPQMELSNGFILHKKELIPTAVETFEGFREVVDAVLTLNNSTSSIGLSSGSNTSRKTISDLQMRKQQYRMRLLASQAAGSTTRSTTTLKTSTTSVSTTSEATSPSKTSRHFDRFTADLNSSTRARPTPPMAPPIMSPSTEFSTTTTEEEDVTGVIRSSSIASRATTYGFFTATKPSAFLDPECRDMRYSCGFWLKNNKQVCEEQQSFMRAQCAYTCKFCTSFIKRH |
| Enzyme Length | 664 |
| Uniprot Accession Number | Q9XU75 |
| Absorption | |
| Active Site | ACT_SITE 437; /note=Proton donor/acceptor; /evidence=ECO:0000250|UniProtKB:P00732 |
| Activity Regulation | |
| Binding Site | BINDING 281; /note=Substrate; /evidence=ECO:0000250|UniProtKB:P15085 |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.17.- |
| Enzyme Function | FUNCTION: May play a role in processing or organization of cuticle collagen proteins, including rol-6 and col-19. {ECO:0000269|PubMed:21094156}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Binding site (1); Chain (1); Compositional bias (2); Disulfide bond (3); Domain (1); Metal binding (3); Mutagenesis (2); Propeptide (1); Region (4); Signal peptide (1) |
| Keywords | Carboxypeptidase;Cytoplasmic vesicle;Disulfide bond;Hydrolase;Metal-binding;Metalloprotease;Protease;Reference proteome;Secreted;Signal;Zinc;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasmic vesicle {ECO:0000269|PubMed:21094156}. Secreted {ECO:0000305|PubMed:21094156}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..23; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 10778742; 14551910; 17164286; 19343510; 21085631; 21177967; 22267497; 22286215; 22347378; 22560298; 23800452; 24884423; 25487147; 6593563; |
| Motif | |
| Gene Encoded By | |
| Mass | 75,153 |
| Kinetics | |
| Metal Binding | METAL 219; /note=Zinc; catalytic; /evidence=ECO:0000250|UniProtKB:P15085; METAL 222; /note=Zinc; catalytic; /evidence=ECO:0000250|UniProtKB:P15085; METAL 361; /note=Zinc; catalytic; /evidence=ECO:0000250|UniProtKB:P15085 |
| Rhea ID | |
| Cross Reference Brenda |