| IED ID |
IndEnz0002013362 |
| Enzyme Type ID |
protease013362 |
| Protein Name |
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein
|
| Gene Name |
wfikkn zgc:85816 |
| Organism |
Danio rerio (Zebrafish) (Brachydanio rerio) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Metazoa
Eumetazoa
Bilateria
Deuterostomia
Chordata
Craniata
Vertebrata
Gnathostomata (jawed vertebrates)
Teleostomi
Euteleostomi
Actinopterygii
Actinopteri
Neopterygii
Teleostei
Osteoglossocephalai
Clupeocephala
Otomorpha
Ostariophysi
Otophysi
Cypriniphysae
Cypriniformes (carps and others)
Cyprinoidei
Danionidae
Danioninae
Danio
Danio rerio (Zebrafish) (Brachydanio rerio)
|
| Enzyme Sequence |
MHSSALLVLLCLWPAAALGPSDADHAGVCPNQLNLHLWVDAQSTCERECHSDQDCSSSEKCCTNVCGLLSCVASRVSDGSSEGQWAAGGSGGSAVSCEGFECRQQGAVCELWEGQPVCKCQDLCGSEPSFTCASDGLTYFNRCYMDAEACLQGVELSEVTCRFHLSSPNSSPLPQDPTPPPAPTDADTQTSAPTLYSSPQQQVTYLGGTVSFHCDVIGQPKPEVTWEKQSDEQEQVVMRADQMFGNVVITSIGQLVVYNAQVWDSGIYSCVARNSAGVLRADFSLSVVSHADQDFFDDPAAGLPLGRPFSPADCSAAVERGDCGEKRVDWFFDPARGSCHTFTHGGCEGRNRFHTFEECRASCQREGQAVCSLPAVQGPCRHWQARWFYNSLTERCEAFLYGGCSGNKNSFGTRRECDAHCPTHRPRPCRSCRHRGRIMDTLCSSDFAIVGQLTELIQELDSGMARFHLQQVLRDEKMGLQLFRTQHLEVLLPQVDWSCPCPNITQLQLPLLVMGVVQDGAAILLPHSYARPVSERRLMKIHEALDKNICGTLRRLQD |
| Enzyme Length |
558 |
| Uniprot Accession Number |
Q6NUX0 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity (By similarity). {ECO:0000250}. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Alternative sequence (1); Chain (1); Compositional bias (1); Disulfide bond (17); Domain (6); Erroneous initiation (1); Glycosylation (1); Region (1); Sequence conflict (2); Signal peptide (1) |
| Keywords |
Alternative splicing;Disulfide bond;Glycoprotein;Immunoglobulin domain;Metalloenzyme inhibitor;Metalloprotease inhibitor;Protease inhibitor;Reference proteome;Repeat;Secreted;Serine protease inhibitor;Signal |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Secreted {ECO:0000250}. |
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
SIGNAL 1..17; /evidence=ECO:0000255 |
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
|
| Gene Encoded By |
|
| Mass |
61,154 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
|