| IED ID | IndEnz0002013367 |
| Enzyme Type ID | protease013367 |
| Protein Name |
Zinc metalloproteinase-disintegrin-like scutiarin EC 3.4.24.- Snake venom metalloproteinase SVMP Fragment |
| Gene Name | |
| Organism | Crotalus scutulatus scutulatus (Mojave rattlesnake) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Sauropsida Sauria (diapsids) Lepidosauria (lepidosaurs) Squamata (squamates) Bifurcata (split-tongued squamates) Unidentata Episquamata Toxicofera Serpentes (snakes) Colubroidea Viperidae Crotalinae (pit vipers) Crotalus Crotalus scutulatus (Mojave rattlesnake) Crotalus scutulatus scutulatus (Mojave rattlesnake) |
| Enzyme Sequence | NPCCDAATCKLKSGSQCGHGDCCEQCKFSKSGTECRASMSECDPAEHCTGQSSECPADVFHKNGQPCLDNYGYCYNGNCPIMYHQCYDLFGADVYEAEDSCFERNQKGNYYGYCRKENGNKIPCAPEDVKCGRLYCKDNSPGQNNPCKMFYSNEDEHKGMVLPGTKCADGKVCSNRQ |
| Enzyme Length | 177 |
| Uniprot Accession Number | A2CJE2 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.24.- |
| Enzyme Function | FUNCTION: Snake venom metalloproteinase that impairs hemostasis in the envenomed animal. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Disulfide bond (10); Domain (1); Metal binding (5); Motif (1); Non-terminal residue (2) |
| Keywords | Calcium;Disulfide bond;Glycoprotein;Hemostasis impairing toxin;Hydrolase;Metal-binding;Metalloprotease;Protease;Secreted;Toxin;Zinc |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | PTM: Glycosylated. {ECO:0000250}. |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | MOTIF 41..43; /note=D/ECD-tripeptide |
| Gene Encoded By | |
| Mass | 19,578 |
| Kinetics | |
| Metal Binding | METAL 43; /note=Calcium; /evidence=ECO:0000250; METAL 44; /note=Calcium; via carbonyl oxygen; /evidence=ECO:0000250; METAL 46; /note=Calcium; /evidence=ECO:0000250; METAL 58; /note=Calcium; /evidence=ECO:0000250; METAL 59; /note=Calcium; via carbonyl oxygen; /evidence=ECO:0000250 |
| Rhea ID | |
| Cross Reference Brenda |