Detail Information for IndEnz0002013507
IED ID IndEnz0002013507
Enzyme Type ID protease013507
Protein Name 26S proteasome non-ATPase regulatory subunit 7 homolog A
26S proteasome regulatory subunit RPN8a
AtRPN8a
Protein ASYMMETRIC LEAVES ENHANCER 3
Protein MOV34
AtMOV34
Gene Name RPN8A AE3 MOV34 At5g05780 MJJ3.19
Organism Arabidopsis thaliana (Mouse-ear cress)
Taxonomic Lineage cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress)
Enzyme Sequence MDVIKTQQISARTIEKVVVHPLVLLSIVDHYNRVAKDSSKRVVGVLLGSSSRGVVDVTNSYAVPFEEDDKDPSIWFLDHNYHESMFHMFKRINAKEHVVGWYSTGPKLRENDLDVHALFNGYVPNPVLVIIDVQPKELGIPTKAYYAVEEVKENATQKSQKVFVHVSTEIAAHEVEEIGVEHLLRDVKDTTISTLATEVTAKLTALKGLDARLREIRSYLDLVIEGKLPLNHEILYHLQDVFNLLPNLNVNELVKAFSVKTNDMMLVIYLSSLIRSVIALHNLINNKLLNKEHEKAEDSKPVAIPATS
Enzyme Length 308
Uniprot Accession Number O24412
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins (By similarity). Required for innate immunity. {ECO:0000250, ECO:0000269|PubMed:22577987}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Domain (1); Modified residue (1)
Keywords Acetylation;Alternative splicing;Immunity;Innate immunity;Proteasome;Reference proteome
Interact With
Induction
Subcellular Location
Modified Residue MOD_RES 1; /note=N-acetylmethionine; /evidence=ECO:0000269|PubMed:20516081
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 10363660; 12368493; 17825468; 18805951; 19704803; 20706207; 24529374; 27247031; 29487187;
Motif
Gene Encoded By
Mass 34,728
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda