| IED ID |
IndEnz0002013562 |
| Enzyme Type ID |
protease013562 |
| Protein Name |
Kunitz-type trypsin inhibitor BrTI
|
| Gene Name |
|
| Organism |
Bauhinia rufa (Orchid tree) (Pauletia rufa) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Viridiplantae
Streptophyta
Streptophytina
Embryophyta
Tracheophyta
Euphyllophyta
Spermatophyta
Magnoliopsida
Mesangiospermae
eudicotyledons
Gunneridae
Pentapetalae
rosids
fabids
Fabales
Fabaceae
Cercidoideae
Cercideae
Bauhiniinae
Bauhinia
Bauhinia rufa (Orchid tree) (Pauletia rufa)
|
| Enzyme Sequence |
SVVLDTKGQPVRNAADAYYLEPVARGDGGLALAKVGNEAEPKAVVLDPNHRPGLTVRFETPLRINIIKESFFLNIKFVPSSSESEVWEVRQQYPEGLAVKVTDTKSLVGPFRVEKEGEGYKIVYYPDRGETGLDIGLVHRNEKYYLAVKDGEPFVFKIRKATDE |
| Enzyme Length |
164 |
| Uniprot Accession Number |
P84882 |
| Absorption |
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| Active Site |
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| Activity Regulation |
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| Binding Site |
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| Calcium Binding |
|
| catalytic Activity |
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| DNA Binding |
|
| EC Number |
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| Enzyme Function |
FUNCTION: Inhibitor of trypsin and human plasma kallikrein with a Ki of 2.9 nM and 14.0 nM, respectively. Does not inhibit chymotrypsin, porcine pancreatic elastas, human neutrophil elastase, coagulation factor Xa, human thrombin, porcine pancreatic kallikrein or plasmin. {ECO:0000269|PubMed:16846639}. |
| Temperature Dependency |
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| PH Dependency |
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| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Site (1) |
| Keywords |
Direct protein sequencing;Protease inhibitor;Serine protease inhibitor |
| Interact With |
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| Induction |
|
| Subcellular Location |
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| Modified Residue |
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| Post Translational Modification |
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| Signal Peptide |
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| Structure 3D |
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| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
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| Gene Encoded By |
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| Mass |
18,326 |
| Kinetics |
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| Metal Binding |
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| Rhea ID |
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| Cross Reference Brenda |
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