| IED ID |
IndEnz0002013667 |
| Enzyme Type ID |
protease013667 |
| Protein Name |
Therostasin
|
| Gene Name |
|
| Organism |
Theromyzon tessulatum (Duck leech) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Metazoa
Eumetazoa
Bilateria
Protostomia
Spiralia
Lophotrochozoa
Annelida
Clitellata
Hirudinea (leeches)
Rhynchobdellida
Glossiphoniidae
Theromyzon
Theromyzon tessulatum (Duck leech)
|
| Enzyme Sequence |
MRGLAVLLLVACFCSVAFGDCENTECPRACPGEYEFDEDGCNTCLCKGCNDAQCRIYCPLGFTTDANGCESFCTCNTRETVCQNVVCSGKRVCNPRSGRCE |
| Enzyme Length |
101 |
| Uniprot Accession Number |
Q9NBW4 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Potent inhibitor of factor Xa. It also inhibits trypsin in a weaker manner. {ECO:0000269|PubMed:10852926}. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Domain (2); Signal peptide (1) |
| Keywords |
Direct protein sequencing;Protease inhibitor;Repeat;Secreted;Serine protease inhibitor;Signal |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Secreted. |
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
SIGNAL 1..19; /evidence=ECO:0000269|PubMed:10852926 |
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
|
| Gene Encoded By |
|
| Mass |
10,951 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
|