| IED ID |
IndEnz0002013745 |
| Enzyme Type ID |
protease013745 |
| Protein Name |
Macrocypin-1a
|
| Gene Name |
|
| Organism |
Macrolepiota procera (Parasol mushroom) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Fungi
Dikarya
Basidiomycota
Agaricomycotina
Agaricomycetes
Agaricomycetidae
Agaricales
Agaricaceae
Macrolepiota
Macrolepiota procera (Parasol mushroom)
|
| Enzyme Sequence |
MGFEDGFYTILHLAEGQHPNSKIPGGMYASSKDGKDVPVTAEPLGPQSKIRWWIARDPQAGDDMYTITEFRIDNSIPGQWSRSPVETEVPVYLYDRIKAEETGYTCAWRIQPADHGADGVYHIVGNVRIGSTDWADLREEYGEPQVYMKPVPVIPNVYIPRWFILGYEE |
| Enzyme Length |
169 |
| Uniprot Accession Number |
B9V973 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Inhibits papain and cysteine cathepsin endopeptidases, and also inhibits cathepsins B and H, which exhibit both exopeptidase and endopeptidase activities. {ECO:0000269|PubMed:19678836}. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Beta strand (13); Chain (1); Helix (2); Initiator methionine (1); Mutagenesis (1); Sequence conflict (7) |
| Keywords |
3D-structure;Direct protein sequencing;Protease inhibitor;Thiol protease inhibitor |
| Interact With |
|
| Induction |
|
| Subcellular Location |
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| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
|
| Structure 3D |
X-ray crystallography (1) |
| Cross Reference PDB |
3H6Q;
|
| Mapped Pubmed ID |
- |
| Motif |
|
| Gene Encoded By |
|
| Mass |
19,194 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
|