| IED ID | IndEnz0002013820 |
| Enzyme Type ID | protease013820 |
| Protein Name |
Rhomboid protein 2 EC 3.4.21.- |
| Gene Name | rbd-2 NCU02371 |
| Organism | Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta sordariomyceta Sordariomycetes Sordariomycetidae Sordariales Sordariaceae Neurospora Neurospora crassa Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) |
| Enzyme Sequence | MAAQTLPASGAAVTFNTQRTRAYLLKLPLFTRATVLIIVLTWVLTLVGKSWNWDVKTWGALIPDEIGIATLYRINTFPFIHLNIFHTILNIVAFTPLLERFEHEHGTLTSVALFFGPFATIPGLIYVFVERFILHANTPVMGASMWVFLLLGMEAIRTYKTNPYFTISTYNIPTWITPLLLVVVTAALLPSSSFLGHLAGLLVGYGFGLGYLKFLAPPEWALRFIEGKLNLLGRLPHYVSVDQKTFGRFGVLPSSASSAEAGIPFSGVSGGQRLGP |
| Enzyme Length | 276 |
| Uniprot Accession Number | Q7S4V5 |
| Absorption | |
| Active Site | ACT_SITE 144; /note=Nucleophile; /evidence=ECO:0000250; ACT_SITE 197; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.21.- |
| Enzyme Function | FUNCTION: Probable serine protease. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Transmembrane (6) |
| Keywords | Golgi apparatus;Hydrolase;Membrane;Protease;Reference proteome;Serine protease;Transmembrane;Transmembrane helix |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Golgi apparatus, cis-Golgi network membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 30,386 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |