| IED ID | IndEnz0002013834 |
| Enzyme Type ID | protease013834 |
| Protein Name |
Probable cysteine protease RD19C EC 3.4.22.- RD19-like protein 2 |
| Gene Name | RD19C RDL2 At4g16190 dl4135w |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
| Enzyme Sequence | MDRVVFFFLIAATLLAGSLGSTVISGEVTDGFVNPIRQVVPEENDEQLLNAEHHFTLFKSKYEKTYATQVEHDHRFRVFKANLRRARRNQLLDPSAVHGVTQFSDLTPKEFRRKFLGLKRRGFRLPTDTQTAPILPTSDLPTEFDWREQGAVTPVKNQGMCGSCWSFSAIGALEGAHFLATKELVSLSEQQLVDCDHECDPAQANSCDSGCSGGLMNNAFEYALKAGGLMKEEDYPYTGRDHTACKFDKSKIVASVSNFSVVSSDEDQIAANLVQHGPLAIAINAMWMQTYIGGVSCPYVCSKSQDHGVLLVGFGSSGYAPIRLKEKPYWIIKNSWGAMWGEHGYYKICRGPHNMCGMDTMVSTVAAVHTSPK |
| Enzyme Length | 373 |
| Uniprot Accession Number | Q9SUL1 |
| Absorption | |
| Active Site | ACT_SITE 164; /evidence=ECO:0000255|PROSITE-ProRule:PRU10088; ACT_SITE 307; /evidence=ECO:0000255|PROSITE-ProRule:PRU10089; ACT_SITE 334; /evidence=ECO:0000255|PROSITE-ProRule:PRU10090 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.22.- |
| Enzyme Function | FUNCTION: Probable thiol protease. {ECO:0000250|UniProtKB:P43297}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Disulfide bond (3); Glycosylation (1); Propeptide (1); Signal peptide (1) |
| Keywords | Disulfide bond;Glycoprotein;Hydrolase;Protease;Reference proteome;Signal;Thiol protease;Vacuole;Zymogen |
| Interact With | |
| Induction | INDUCTION: By drought stress. {ECO:0000269|PubMed:12102506}. |
| Subcellular Location | SUBCELLULAR LOCATION: Lytic vacuole {ECO:0000269|PubMed:18708476}. Note=Predominantly vacuolar. From the Golgi apparatus, probably transported to the lytic vacuole (LV) in clathrin-coated vesicles (CCVs) via the prevacuolar compartment (PVC). {ECO:0000269|PubMed:18708476}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..20; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 12609038; 12609039; 12805589; 14585825; 14617064; 14697270; 15047898; 15208337; 15539469; 15837708; 16500996; 16581873; 16873489; 17885809; 18053238; 18650403; 22253603; 23738689; 27247031; 32321832; |
| Motif | |
| Gene Encoded By | |
| Mass | 41,264 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |