| IED ID | IndEnz0002013974 |
| Enzyme Type ID | protease013974 |
| Protein Name |
Kunitz-type serine protease inhibitor 6 BmTI-6 Fragment |
| Gene Name | |
| Organism | Rhipicephalus microplus (Cattle tick) (Boophilus microplus) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Chelicerata Arachnida Acari Parasitiformes Ixodida (ticks) Ixodoidea Ixodidae (hardbacked ticks) Rhipicephalinae Rhipicephalus Boophilus Rhipicephalus microplus (Cattle tick) (Boophilus microplus) |
| Enzyme Sequence | VDFETYCKPTYDSGPCKGYFPRWWFNVKTGQCEEFIYGGCQGNKNNHVTRKECETRCLRKQLSRLHFSPPVDQYPYGDTERSNEEVPEYPPVHLNDSLEVSAVMNQRPLRNYTKQHKPNVTSDFSAISLTSGVDFETYCKPTHDRGPCKAYIPRWWFNVKTGQCEQFIYGGCQGNKNNYETKSICETNCLRRQLSELGVSADVHYRKHWNETKYSPNVTVEYPAVHFNVTLNPVCNEPKYPELCKGYFPRYYYNSRSKTCKKFIYGGCQSNGNNFLTLEECENTCLVDLQV |
| Enzyme Length | 291 |
| Uniprot Accession Number | P83606 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Inhibits trypsin and plasmin. Does not inhibit human plasma kallikrein, chymotrypsin, human neutrophil elastase, factor Xa, factor XIIa or thrombin. {ECO:0000269|PubMed:18502587, ECO:0000269|Ref.3}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Disulfide bond (9); Domain (3); Glycosylation (6); Non-terminal residue (1); Sequence conflict (3); Site (3) |
| Keywords | Direct protein sequencing;Disulfide bond;Glycoprotein;Protease inhibitor;Repeat;Secreted;Serine protease inhibitor |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 33,847 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |