| IED ID | IndEnz0002014165 |
| Enzyme Type ID | protease014165 |
| Protein Name |
Probable Xaa-Pro aminopeptidase PEPP EC 3.4.11.9 Aminoacylproline aminopeptidase Prolidase |
| Gene Name | PEPP Lema_P059740 |
| Organism | Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta dothideomyceta Dothideomycetes Pleosporomycetidae Pleosporales Pleosporineae Leptosphaeriaceae Leptosphaeria Leptosphaeria maculans species complex Leptosphaeria maculans (Blackleg fungus) (Phoma lingam) Leptosphaeria maculans 'brassicae' group Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) |
| Enzyme Sequence | MTRTMVVTVRFCTFLINVDDEWDANPWLPEQVSLDPRPPLKHRPKLNFDMSAFSSRGMRLARTLQRRYTRRPLPTYQQPTPFTFRILPAEDREWCSISTMAIAENYEDVLKGKYPAKEHARKVAKWIIEKGGDKNGTIYLEAQKQKLNEDNDGEAPFRQRRYFFYLSGCELPDSYLTYEIPNDRLTLFIPPVEPEEVIWSGLPMSVDEAKAKYDIDDCKTTRDINAHLTSTSESAQSTIYAIPEQVSDNITFLSYKDKEFKQLKPAIEYCRVTKTDYEIALIRKANEISTAAHIAVMKAASKAKNECELEAVFLKSCVERNAKNQAYHSIVAAGENGATLHYVNNAAPISEQNLLLLDAGCEVDCYASDITRTFPIKGHFNEESLAIYKIVLDMQHQCINALKAGVLWDSIHELAHKIAIKGLLDLGILKGDADAIFKARASVAFFPHGLGHYLGMDTHDTGGNANYADKDVMFRYLRVRGTLPERSVITVEPGIYFCRFIIEPYLKDEEKKQFFDEKVLEKYWSVGGVRIEDNILITKEGIENLTPTPKEVDEITALVQSA |
| Enzyme Length | 562 |
| Uniprot Accession Number | E4ZHV7 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.; EC=3.4.11.9; |
| DNA Binding | |
| EC Number | 3.4.11.9 |
| Enzyme Function | FUNCTION: Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Metal binding (6) |
| Keywords | Aminopeptidase;Hydrolase;Manganese;Metal-binding;Metalloprotease;Protease;Reference proteome |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 63,896 |
| Kinetics | |
| Metal Binding | METAL 358; /note=Manganese 2; /evidence=ECO:0000250; METAL 369; /note=Manganese 1; /evidence=ECO:0000250; METAL 369; /note=Manganese 2; /evidence=ECO:0000250; METAL 492; /note=Manganese 1; /evidence=ECO:0000250; METAL 532; /note=Manganese 1; /evidence=ECO:0000250; METAL 532; /note=Manganese 2; /evidence=ECO:0000250 |
| Rhea ID | |
| Cross Reference Brenda |