| IED ID | IndEnz0002014186 |
| Enzyme Type ID | protease014186 |
| Protein Name |
Aspartic proteinase CDR1 EC 3.4.23.- Protein CONSTITUTIVE DISEASE RESISTANCE 1 |
| Gene Name | CDR1 At5g33340 F19N2.60 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
| Enzyme Sequence | MASLFSSVLLSLCLLSSLFLSNANAKPKLGFTADLIHRDSPKSPFYNPMETSSQRLRNAIHRSVNRVFHFTEKDNTPQPQIDLTSNSGEYLMNVSIGTPPFPIMAIADTGSDLLWTQCAPCDDCYTQVDPLFDPKTSSTYKDVSCSSSQCTALENQASCSTNDNTCSYSLSYGDNSYTKGNIAVDTLTLGSSDTRPMQLKNIIIGCGHNNAGTFNKKGSGIVGLGGGPVSLIKQLGDSIDGKFSYCLVPLTSKKDQTSKINFGTNAIVSGSGVVSTPLIAKASQETFYYLTLKSISVGSKQIQYSGSDSESSEGNIIIDSGTTLTLLPTEFYSELEDAVASSIDAEKKQDPQSGLSLCYSATGDLKVPVITMHFDGADVKLDSSNAFVQVSEDLVCFAFRGSPSFSIYGNVAQMNFLVGYDTVSKTVSFKPTDCAKM |
| Enzyme Length | 437 |
| Uniprot Accession Number | Q6XBF8 |
| Absorption | |
| Active Site | ACT_SITE 108; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094; ACT_SITE 319; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.23.- |
| Enzyme Function | FUNCTION: Involved in salicylic acid-dependent inducible resistance responses. May release an endogenous peptide elicitor required for the activation of inducible resistance mechanisms. Possesses protease activity in vitro. {ECO:0000269|PubMed:14765119}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Domain (1); Erroneous termination (1); Glycosylation (1); Mutagenesis (2); Propeptide (1); Signal peptide (1) |
| Keywords | Apoplast;Aspartyl protease;Glycoprotein;Hydrolase;Plant defense;Protease;Reference proteome;Secreted;Signal;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted, extracellular space, apoplast {ECO:0000269|PubMed:14765119}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..25; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 14697270; 15231262; 16299181; 17650510; 20226671; 21985276; 22995285; 29086445; 32629813; |
| Motif | |
| Gene Encoded By | |
| Mass | 46,819 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |