| IED ID | IndEnz0002014212 |
| Enzyme Type ID | protease014212 |
| Protein Name |
Membrane alanyl aminopeptidase EC 3.4.11.- Aminopeptidase N-like protein CryIA C receptor Fragment |
| Gene Name | |
| Organism | Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Mandibulata Pancrustacea Hexapoda Insecta Dicondylia Pterygota (winged insects) Neoptera Endopterygota Amphiesmenoptera Lepidoptera (butterflies and moths) Glossata Neolepidoptera Heteroneura Ditrysia Obtectomera Bombycoidea (hawk-moths) Sphingidae (hawkmoths) Sphinginae (small-eyed sphinx moth) Sphingini Manduca Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) |
| Enzyme Sequence | FTIFLGVALLQGVLTLSPIPVPEEEWAEFSRMLRDPSYRLPTTTRPRHYAVTLTPYFDVVPAGVSGLTTFSFDGEVTIYISPTQANVNEIVLHCNDLTIQSLRVTYVSGNSEVDITATGQTFTCEMPYSFLRIRTSTPLVMNQEYIIRSTFRGNLQTNMRGFYRSWYVDRTGKRWMATTQFQPGHARQAFPCYDEPGFKATFDITMNREADFSPTISNMPIRATTTLTNGRISETFFTTPLTSTYLLAFIVSHYQVISNNNNAARPFRIYARNNVGSQGDWSLEMGEKLLLAMENYTAIPYYTMAQNLDMKQAAIPDFSAGAMENWGLLTYREALILYDPLNSNHHYRQRVANIVSHEIAHMWFGNLVTCAWWDNLWLNEGFARFSQYYLTATVDPELGYEIRFIPEQLQVAMFSDSVDSAHALTDTSVNDPVAVSAHFSTITYARGAAILRMTQHLLSYDTFVKGLRQYLRARQFDVAEPYHLFSALDAAAAEDNALAAYRGITIDAYFRTWSEKAGHPLLSVTVDHESGRMTLVQARWERNTGVSRFPGLWHIPITWTRAGAPDFENLKPSQVMTGQSLVIDRGTRGQEWVIFNKQVSGFYRVNYDNTTWGLITRALRSANRTVIHELSRSQIVDDVFQLARSGVMSYQRALNILSYLRFEDAYAPWLSAISGFNWVIRRFAHDAANLQTLQNQIIGLSEAVVARLGFTEVSGGTYMTDLQRLHVMQFLCNVGHQQCIDAGRQNFLNWRNGSFIPANMRPWVYCTGLRYGSAEDFNYFWNRYIVEDLSNEKVVMLEAAGCTRDQASLEKFLNAIVSGNDDVRPQDHSSALSSAITSNDVNTMRAFDWLTKNVDQITRTLGSITSPLNTITSRLLTEAQMTQVQTWLDANRNTIGAAYNTGVNGIATSRANLQWSANRMSEFLRFFETGFVDDVPSEATTVAPPAETTVTPSTFPPTVAPATTPAPGSGNIAALSVVSLLVTLAINMVA |
| Enzyme Length | 990 |
| Uniprot Accession Number | Q11001 |
| Absorption | |
| Active Site | ACT_SITE 358; /note=Proton acceptor; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.11.- |
| Enzyme Function | FUNCTION: Binds to the B.thuringiensis toxin, CryIA(C). |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Glycosylation (4); Lipidation (1); Metal binding (3); Non-terminal residue (1); Propeptide (2); Region (1); Signal peptide (1); Site (1) |
| Keywords | Aminopeptidase;Cell membrane;Direct protein sequencing;GPI-anchor;Glycoprotein;Hydrolase;Lipoprotein;Membrane;Metal-binding;Metalloprotease;Protease;Signal;Zinc |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor, GPI-anchor. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL <1..15; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 111,294 |
| Kinetics | |
| Metal Binding | METAL 357; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095; METAL 361; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095; METAL 380; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095 |
| Rhea ID | |
| Cross Reference Brenda |