| IED ID | IndEnz0002014286 |
| Enzyme Type ID | protease014286 |
| Protein Name |
Sensor protein DegM EC 2.7.13.3 |
| Gene Name | degM |
| Organism | Bacillus sp. (strain B21-2) |
| Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Bacillales Bacillaceae Bacillus unclassified Bacillus (in: Bacteria) Bacillus sp. (strain B21-2) |
| Enzyme Sequence | MSGAVLLCLFFSINVGNIQWDLRYIPILLAFLYGGKRAGWGVAAIAVVGRIGQGGDLFLLGVVLIVLTALFYALCVNRFYMLPPRWSRIRYASLLVILPATIQTFGTLYLINYENHLSESWVAGWLYIVFLVVTVVLVTYLFETLLEKERIVAELVATEKDFTKGELAASIAHEVRNPLTVVKGFVQLLSEDKQHAEYHKLILSELDRAESIIYEFLNTTRPQTNATFHLNETAREVVALLTPYAQERSIQLTIGTCEQAIVNGNENKVKQALMNFVKNGIEASNEGDTVTIQLDRLKDRAQIEINDNGVGMSRQQLKQLGTAYFTTKESGNGIGTMVSIRIVEMMNGMVTFKSKPGKGTKVVLSLPIEKENE |
| Enzyme Length | 373 |
| Uniprot Accession Number | Q03069 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.; EC=2.7.13.3; |
| DNA Binding | |
| EC Number | 2.7.13.3 |
| Enzyme Function | FUNCTION: Involved in a sensory transduction pathway that enhances the production of minor proteases. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Domain (1); Modified residue (1); Transmembrane (4) |
| Keywords | ATP-binding;Cell membrane;Kinase;Membrane;Nucleotide-binding;Phosphoprotein;Transferase;Transmembrane;Transmembrane helix;Two-component regulatory system |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. |
| Modified Residue | MOD_RES 173; /note=Phosphohistidine; by autocatalysis; /evidence=ECO:0000255|PROSITE-ProRule:PRU00107 |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 41,614 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |