Detail Information for IndEnz0002014331
IED ID IndEnz0002014331
Enzyme Type ID protease014331
Protein Name Cysteine protease inhibitor 1
P340
P34021
PCPI 8.3
Gene Name
Organism Solanum tuberosum (Potato)
Taxonomic Lineage cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae asterids lamiids Solanales Solanaceae Solanoideae Solaneae Solanum Solanum tuberosum (Potato)
Enzyme Sequence MKSINILSFLLLSSTLSLVAFARSFTSENPIVLPTTCHDDDNLVLPEVYDQDGNPLRIGERYIINNPLLGAGAVYLYNIGNLQCPNAVLQHMSIPQFLGEGTPVVFVRKSESDYGDVVRVMTVVYIKFFVKTTKLCVDQTVWKVNDEQLVVTGGKVGNENDIFKIMKTDLVTPGGSKYVYKLLHCPSHLGCKNIGGNFKNGYPRLVTVDDDKDFIPFVFIKA
Enzyme Length 222
Uniprot Accession Number P20347
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Potent inhibitor of cathepsin l (cysteine protease). Does not inhibit trypsin or chymotrypsin (serine proteases). May protect the plant by inhibiting proteases of invading organisms. {ECO:0000269|PubMed:2401357}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Disulfide bond (2); Frameshift (1); Motif (1); Propeptide (1); Sequence conflict (3); Signal peptide (1)
Keywords Direct protein sequencing;Disulfide bond;Protease inhibitor;Reference proteome;Signal;Thiol protease inhibitor;Vacuole
Interact With
Induction INDUCTION: By wounding. Also expressed in upper non-wounded systemic leaves. {ECO:0000269|Ref.6}.
Subcellular Location SUBCELLULAR LOCATION: Vacuole {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..26; /evidence=ECO:0000250
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif MOTIF 29..34; /note=Vacuolar targeting signal; /evidence=ECO:0000250
Gene Encoded By
Mass 24,684
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda