| IED ID | IndEnz0002014332 |
| Enzyme Type ID | protease014332 |
| Protein Name |
Protein ASPARTIC PROTEASE IN GUARD CELL 1 AtASPG1 EC 3.4.23.- |
| Gene Name | ASPG1 At3g18490 MYF24.22 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
| Enzyme Sequence | MAFPRFLSLLAVVTLSLFLTTTDASSRSLSTPPKTNVLDVVSSLQQTQTILSLDPTRSSLTTTKPESLSDPVFFNSSSPLSLELHSRDTFVASQHKDYKSLTLSRLERDSSRVAGIVAKIRFAVEGVDRSDLKPVYNEDTRYQTEDLTTPVVSGASQGSGEYFSRIGVGTPAKEMYLVLDTGSDVNWIQCEPCADCYQQSDPVFNPTSSSTYKSLTCSAPQCSLLETSACRSNKCLYQVSYGDGSFTVGELATDTVTFGNSGKINNVALGCGHDNEGLFTGAAGLLGLGGGVLSITNQMKATSFSYCLVDRDSGKSSSLDFNSVQLGGGDATAPLLRNKKIDTFYYVGLSGFSVGGEKVVLPDAIFDVDASGSGGVILDCGTAVTRLQTQAYNSLRDAFLKLTVNLKKGSSSISLFDTCYDFSSLSTVKVPTVAFHFTGGKSLDLPAKNYLIPVDDSGTFCFAFAPTSSSLSIIGNVQQQGTRITYDLSKNVIGLSGNKC |
| Enzyme Length | 500 |
| Uniprot Accession Number | Q9LS40 |
| Absorption | |
| Active Site | ACT_SITE 180; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094; ACT_SITE 379; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094 |
| Activity Regulation | ACTIVITY REGULATION: Inhibited by pepstatin A. {ECO:0000269|PubMed:22268147}. |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.23.- |
| Enzyme Function | FUNCTION: Aspartic protease involved in drought avoidance through abscisic acid signaling. {ECO:0000269|PubMed:22268147}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Disulfide bond (6); Domain (1); Mutagenesis (2); Sequence conflict (1); Signal peptide (1) |
| Keywords | Aspartyl protease;DNA-binding;Disulfide bond;Endoplasmic reticulum;Hydrolase;Protease;Reference proteome;Signal |
| Interact With | |
| Induction | INDUCTION: Up-regulated by abscisic acid and drought. {ECO:0000269|PubMed:22268147}. |
| Subcellular Location | SUBCELLULAR LOCATION: Endoplasmic reticulum {ECO:0000269|PubMed:22268147}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..24; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 15247402; 15352244; 16377752; 17163439; 18805951; 20118269; 24755512; 28003327; 28627464; 29648652; |
| Motif | |
| Gene Encoded By | |
| Mass | 53,234 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |