IED ID | IndEnz0002014375 |
Enzyme Type ID | protease014375 |
Protein Name |
Two-component response regulator ARR4 Response regulator 1 |
Gene Name | ARR4 ATRR1 IBC7 At1g10470 T10O24.8 |
Organism | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
Enzyme Sequence | MARDGGVSCLRRSEMMSVGGIGGIESAPLDLDEVHVLAVDDSLVDRIVIERLLRITSCKVTAVDSGWRALEFLGLDNEKASAEFDRLKVDLIITDYCMPGMTGYELLKKIKESSNFREVPVVIMSSENVLTRIDRCLEEGAQDFLLKPVKLADVKRLRSHLTKDVKLSNGNKRKLPEDSSSVNSSLPPPSPPLTISPESSPPLTVSTESSDSSPPLSPVEIFSTSPLSSPIDDEDDDVLTSSSEESPIRRQKMRSPGLD |
Enzyme Length | 259 |
Uniprot Accession Number | O82798 |
Absorption | |
Active Site | |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | |
DNA Binding | |
EC Number | |
Enzyme Function | FUNCTION: Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Type-A response regulators seem to act as negative regulators of the cytokinin signaling. Modulates red light signaling through its interaction with the phytochrome B photoreceptor. {ECO:0000269|PubMed:11691995, ECO:0000269|PubMed:14973166, ECO:0000269|PubMed:9482949}. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Chain (1); Compositional bias (1); Domain (1); Modified residue (1); Region (1) |
Keywords | Cytokinin signaling pathway;Nucleus;Phosphoprotein;Reference proteome;Transcription;Transcription regulation;Two-component regulatory system |
Interact With | O80837; P14713 |
Induction | INDUCTION: By low temperature, dehydration, abscisic acid (ABA), cytokinins (BA and zeatin), nitrate and high salinity. Induced by trans-zeatin (PubMed:27274065). {ECO:0000269|PubMed:11115887, ECO:0000269|PubMed:27274065, ECO:0000269|PubMed:9607306, ECO:0000269|PubMed:9634588, ECO:0000269|PubMed:9662428}. |
Subcellular Location | SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:27274065}. |
Modified Residue | MOD_RES 95; /note=4-aspartylphosphate; /evidence=ECO:0000255|PROSITE-ProRule:PRU00169 |
Post Translational Modification | PTM: Two-component system major event consists of a His-to-Asp phosphorelay between a sensor histidine kinase (HK) and a response regulator (RR). In plants, the His-to-Asp phosphorelay involves an additional intermediate named Histidine-containing phosphotransfer protein (HPt). This multistep phosphorelay consists of a His-Asp-His-Asp sequential transfer of a phosphate group between first an His and an Asp of the HK protein, followed by the transfer to a conserved His of the HPt protein and finally the transfer to an Asp in the receiver domain of the RR protein. |
Signal Peptide | |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | 10501033; 11574878; 12054542; 12068096; 15634699; 15995350; 16326927; 16361787; 16407152; 17061125; 17121545; 17545225; 18065689; 18642946; 18723577; 18775970; 18997423; 19682286; 20736450; 21477822; 21699589; 21741261; 22951399; 23124324; 24423196; 24443518; 25643735; 25914704; 29180814; 33051300; 9771897; 9804162; |
Motif | |
Gene Encoded By | |
Mass | 28,297 |
Kinetics | |
Metal Binding | |
Rhea ID | |
Cross Reference Brenda |