| IED ID | IndEnz0002014498 |
| Enzyme Type ID | protease014498 |
| Protein Name |
BNIP3 homolog CbBNIP3 Daf-16/FOXO controlled germline tumor affecting |
| Gene Name | dct-1 CBG16854 |
| Organism | Caenorhabditis briggsae |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Nematoda (roundworms) Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis Caenorhabditis briggsae |
| Enzyme Sequence | MLDIKKKINFANVSGEKTDESSSSSAQQSSEQQQAAQPLAPQQTTPTAKATNPFITPMTESTPGMSESWVELAPSRTSLCSSVDINMVIIDEKDKDSRLSPVSIAQSPHVEFESLEQVKYKLVREMLPPGKNTDWMWDWSSRPENTPPKTIRMVQYGSNLTTPPNSPEPEMSQYMPYESDSLFNVRVVFGFLVTNIFSFVVGAAVGFAVCRKIIKHHRHY |
| Enzyme Length | 220 |
| Uniprot Accession Number | A8XPY4 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Initiates apoptosis in a BH3-independent mechanism possibly by recruiting ced-3 to mitochondria and other cytoplasmic membranes. Has a role in lifespan and tumor growth (By similarity). {ECO:0000250|UniProtKB:Q09969}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Compositional bias (1); Region (2); Transmembrane (1) |
| Keywords | Apoptosis;Membrane;Mitochondrion;Reference proteome;Transmembrane;Transmembrane helix;Ubl conjugation |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}. |
| Modified Residue | |
| Post Translational Modification | PTM: Ubiquitinated and degraded by the proteasome. {ECO:0000250|UniProtKB:Q09969}. |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 24,633 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |