| IED ID |
IndEnz0002014506 |
| Enzyme Type ID |
protease014506 |
| Protein Name |
Alpha-1-antitrypsin-like protein GS55-MS
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| Gene Name |
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| Organism |
Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Metazoa
Eumetazoa
Bilateria
Deuterostomia
Chordata
Craniata
Vertebrata
Gnathostomata (jawed vertebrates)
Teleostomi
Euteleostomi
Sarcopterygii
Dipnotetrapodomorpha
Tetrapoda
Amniota
Mammalia
Theria
Eutheria
Boreoeutheria
Euarchontoglires
Glires (Rodents and rabbits)
Rodentia
Sciuromorpha (squirrels)
Sciuridae
Xerinae
Marmotini
Ictidomys (lined ground squirrels)
Ictidomys tridecemlineatus (Thirteen-lined ground squirrel) (Spermophilus tridecemlineatus)
|
| Enzyme Sequence |
MPSSISWGLLLLAGLSCLVAGSLAEDAQETGASKHDQEHPASHRIAPNLAEFALSLYRVLAHESNTTNIFFSPVSIAMALASLSLGTKADTHTQIMEGLGFNLTETAESDIHQGFQHLLQTLNKPNSQLQLTTGNGLFIDHNLKLLDKFLQDVKNLYHSEAFSTDFTNTEEAKKQINTYVEKGTQGKIVDLVKDLNRDSVLALVNYIFFKGKWEKPFEVDHTKEEDFHVDQVTTVRVPMMNRMGMFEVHYCSTLASWVLQMDYLGNATAIFLLPDEGKLQHLEDTITKEILAKFLKNRESSSVNLHFPKLNISGTMDLKPVLTRLGITNVFSYKADLSGITEDDPLRVSQALHKAVLTIDERGTEAAGATFLEMMPMSLPPEVKFDKPFLVVIIEHSTKSPLFVGKVVNPTLH |
| Enzyme Length |
413 |
| Uniprot Accession Number |
O54761 |
| Absorption |
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| Active Site |
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| Activity Regulation |
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| Binding Site |
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| Calcium Binding |
|
| catalytic Activity |
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| DNA Binding |
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| EC Number |
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| Enzyme Function |
FUNCTION: Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin (By similarity). {ECO:0000250}. |
| Temperature Dependency |
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| PH Dependency |
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| Pathway |
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| nucleotide Binding |
|
| Features |
Chain (1); Glycosylation (3); Region (1); Signal peptide (1); Site (1) |
| Keywords |
Glycoprotein;Protease inhibitor;Reference proteome;Secreted;Serine protease inhibitor;Signal |
| Interact With |
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| Induction |
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| Subcellular Location |
SUBCELLULAR LOCATION: Secreted {ECO:0000250}. |
| Modified Residue |
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| Post Translational Modification |
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| Signal Peptide |
SIGNAL 1..24; /evidence=ECO:0000255 |
| Structure 3D |
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| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
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| Gene Encoded By |
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| Mass |
45,954 |
| Kinetics |
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| Metal Binding |
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| Rhea ID |
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| Cross Reference Brenda |
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