| IED ID | IndEnz0002014510 |
| Enzyme Type ID | protease014510 |
| Protein Name |
Actinidain Actinidin EC 3.4.22.14 Allergen Act d 1 allergen Act d 1 |
| Gene Name | |
| Organism | Actinidia deliciosa (Kiwi) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae asterids Ericales Actinidiaceae Actinidia Actinidia deliciosa (Kiwi) |
| Enzyme Sequence | MGLPKSFVSMSLLFFSTLLILSLAFNAKNLTQRTNDEVKAMYESWLIKYGKSYNSLGEWERRFEIFKETLRFIDEHNADTNRSYKVGLNQFADLTDEEFRSTYLGFTSGSNKTKVSNRYEPRVGQVLPSYVDWRSAGAVVDIKSQGECGGCWAFSAIATVEGINKIVTGVLISLSEQELIDCGRTQNTRGCNGGYITDGFQFIINNGGINTEENYPYTAQDGECNLDLQNEKYVTIDTYENVPYNNEWALQTAVTYQPVSVALDAAGDAFKHYSSGIFTGPCGTAIDHAVTIVGYGTEGGIDYWIVKNSWDTTWGEEGYMRILRNVGGAGTCGIATMPSYPVKYNNQNHPKPYSSLINPPAFSMSKDGPVGVDDGQRYSA |
| Enzyme Length | 380 |
| Uniprot Accession Number | A5HII1 |
| Absorption | |
| Active Site | ACT_SITE 151; /evidence=ECO:0000250|UniProtKB:P00785; ACT_SITE 288; /evidence=ECO:0000250|UniProtKB:P00785; ACT_SITE 308; /evidence=ECO:0000250|UniProtKB:P00785 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Specificity close to that of papain.; EC=3.4.22.14; Evidence={ECO:0000250|UniProtKB:P00785}; |
| DNA Binding | |
| EC Number | 3.4.22.14 |
| Enzyme Function | FUNCTION: Cysteine protease responsible for the cleavage of kiwellin into kissper and KiTH. {ECO:0000269|PubMed:18442249}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Disulfide bond (3); Frameshift (1); Propeptide (1); Sequence conflict (17); Signal peptide (1) |
| Keywords | Allergen;Direct protein sequencing;Disulfide bond;Hydrolase;Protease;Signal;Thiol protease;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..24; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 42,110 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda | 3.4.22.14; |