| IED ID | IndEnz0002014571 |
| Enzyme Type ID | protease014571 |
| Protein Name |
Aspartic protease Bla g 2 EC 3.4.23.- Allergen Bla g II allergen Bla g 2 |
| Gene Name | |
| Organism | Blattella germanica (German cockroach) (Blatta germanica) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Mandibulata Pancrustacea Hexapoda Insecta Dicondylia Pterygota (winged insects) Neoptera Polyneoptera Dictyoptera Blattodea (cockroaches) Blaberoidea Ectobiidae (German cockroach family) Blattellinae Blattella Blattella germanica (German cockroach) (Blatta germanica) |
| Enzyme Sequence | MIGLKLVTVLFAVATITHAAELQRVPLYKLVHVFINTQYAGITKIGNQNFLTVFDSTSCNVVVASQECVGGACVCPNLQKYEKLKPKYISDGNVQVKFFDTGSAVGRGIEDSLTISNLTTSQQDIVLADELSQEVCILSADVVVGIAAPGCPNALKGKTVLENFVEENLIAPVFSIHHARFQDGEHFGEIIFGGSDWKYVDGEFTYVPLVGDDSWKFRLDGVKIGDTTVAPAGTQAIIDTSKAIIVGPKAYVNPINEAIGCVVEKTTTRRICKLDCSKIPSLPDVTFVINGRNFNISSQYYIQQNGNLCYSGFQPCGHSDHFFIGDFFVDHYYSEFNWENKTMGFGRSVESV |
| Enzyme Length | 352 |
| Uniprot Accession Number | P54958 |
| Absorption | |
| Active Site | ACT_SITE 55; /evidence=ECO:0000250; ACT_SITE 239; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.23.- |
| Enzyme Function | FUNCTION: Functions as a digestive enzyme in the cockroach. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Beta strand (27); Chain (1); Disulfide bond (5); Domain (1); Glycosylation (3); Helix (8); Metal binding (4); Propeptide (1); Sequence conflict (5); Signal peptide (1); Turn (2) |
| Keywords | 3D-structure;Allergen;Aspartyl protease;Direct protein sequencing;Disulfide bond;Glycoprotein;Hydrolase;Metal-binding;Protease;Signal;Zinc;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..19; /evidence=ECO:0000255 |
| Structure 3D | X-ray crystallography (4) |
| Cross Reference PDB | 1YG9; 2NR6; 3LIZ; 4RLD; |
| Mapped Pubmed ID | 21789239; |
| Motif | |
| Gene Encoded By | |
| Mass | 38,558 |
| Kinetics | |
| Metal Binding | METAL 178; /note=Zinc; METAL 186; /note=Zinc; METAL 326; /note=Zinc; METAL 330; /note=Zinc |
| Rhea ID | |
| Cross Reference Brenda |